Natural Products Research Group, Department of Chemistry, University of Surrey, Guildford, GU2 7XH, United Kingdom.
Nat Prod Rep. 2013 Sep;30(9):1165-210. doi: 10.1039/c3np70008a. Epub 2013 Jul 29.
The Hyacinthaceae (sensu APGII), with approximately 900 species in about 70 genera, can be divided into three main subfamilies, the Hyacinthoideae, the Urgineoideae and the Ornithogaloideae, with a small fourth subfamily the Oziroëoideae, restricted to South America. The plants included in this family have long been used in traditional medicine for a wide range of medicinal applications. This, together with some significant toxicity to livestock has led to the chemical composition of many of the species being investigated. The compounds found are, for the most part, subfamily-restricted, with homoisoflavanones and spirocyclic nortriterpenoids characterising the Hyacinthoideae, bufadienolides characterising the Urgineoideae, and cardenolides and steroidal glycosides characterising the Ornithogaloideae. The phytochemical profiles of 38 genera of the Hyacinthaceae will be discussed as well as any biological activity associated with both crude extracts and compounds isolated. The Hyacinthaceae of southern Africa were last reviewed in 2000 (T. S. Pohl, N. R. Crouch and D. A. Mulholland, Curr. Org. Chem., 2000, 4, 1287-1324; ref. 1); the current contribution considers the family at a global level.
风信子科（APGII 系统）约有 900 种，分属 70 余属，可分为三个主要的亚科，即风信子亚科、喇叭兰亚科和蓝星花亚科，还有一个小的第四亚科，即奥孜罗埃亚科，仅限于南美洲。该科植物长期以来一直被用于传统医学，具有广泛的药用用途。这一点，再加上对牲畜的一些显著毒性，导致许多物种的化学成分受到了研究。发现的化合物在大多数情况下是亚科特有的，同型异黄酮和螺环三萜类化合物是风信子亚科的特征，蟾蜍毒是喇叭兰亚科的特征，而强心苷和甾体糖苷是蓝星花亚科的特征。本文将讨论 38 个风信子科属的植物化学特征，以及与粗提取物和分离化合物相关的任何生物活性。2000 年对南非的风信子科植物进行了最后一次综述（T. S. Pohl、N. R. Crouch 和 D. A. Mulholland，Curr. Org. Chem.，2000，4，1287-1324；参考文献 1）；本研究在全球范围内对该科进行了探讨。
