Nielsen Niels Peter, Ringström Roland, Wiig Elisabeth H, Minthon Lennart
Department of Psychiatry, Hvidovre Hospital, Copenhagen, Denmark.
Am J Alzheimers Dis Other Demen. 2007 Jun-Jul;22(3):202-10. doi: 10.1177/1089253206300417.
Associations between A Quick Test of Cognitive Speed (AQT) perceptual and cognitive speed and neuropsychological tests, including the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III), Mini Mental State Examination (MMSE), and the Trail Making Test (TMT), were evaluated in 41 neuropsychiatric patients. Neuropsychological and neurological tests, including CT scan, were administered to all of the patients. AQT was also administered to 75 controls. All AQT means differed significantly for patients and controls. Dual-dimension naming time means in the patient group were in the atypical range and indicated generally reduced cognitive speed, whereas controls performed in the normal range. In the patient group, WAIS-III verbal, performance, and full-scale IQ means were in the normal range. AQT perceptual and cognitive speed correlated negatively with WAIS-III P IQ and MMSE scores, and the relationships were nonlinear. The findings support that AQT dual-dimension naming evaluates cognitive speed (i.e., attention, set shifting, working memory) and can be used for first-line or complementary screening for mild or progressive cognitive impairments.
在41名神经精神疾病患者中,评估了认知速度快速测试(AQT)的感知和认知速度与神经心理学测试之间的关联,这些神经心理学测试包括韦氏成人智力量表第三版(WAIS-III)、简易精神状态检查表(MMSE)和连线测验(TMT)。对所有患者均进行了神经心理学和神经学测试,包括CT扫描。还对75名对照者进行了AQT测试。患者和对照者的所有AQT均值均存在显著差异。患者组的双维度命名时间均值处于非典型范围,表明认知速度总体下降,而对照者的表现处于正常范围。在患者组中,WAIS-III的言语、操作和全量表智商均值处于正常范围。AQT的感知和认知速度与WAIS-III的操作智商和MMSE评分呈负相关,且这种关系是非线性的。研究结果支持AQT双维度命名可评估认知速度(即注意力、定势转换、工作记忆),可用于轻度或进行性认知障碍的一线或辅助筛查。