对接受类固醇治疗的杜氏肌营养不良症患者的肌肉力量和运动能力进行量化评估。
Quantification of muscle strength and motor ability in patients with Duchenne muscular dystrophy on steroid therapy.
作者信息
Parreira Samara Lamounier Santana, Resende Maria Bernadete Dutra, Della Corte Peduto Marília, Marie Suely Kazue Nagahashi, Carvalho Mary Souza, Reed Umbertina Conti
机构信息
Department of Neurology, Medical School, University of São Paulo, São Paulo, SP, Brazil.
出版信息
Arq Neuropsiquiatr. 2007 Jun;65(2A):245-50. doi: 10.1590/s0004-282x2007000200011.
OBJECTIVE
An assessment protocol was applied to quantify and describe muscular strength and motor abilities of 32 patients with Duchenne muscular dystrophy (DMD), aged between 5 and 12 years on steroid therapy.
METHOD
Assessments were made monthly for the first six months and with intervals of two months thereafter until the 14-month end point. The tests employed included: the Medical Research Council (MRC) scale; the Hammersmith motor ability score; maximum weight lift; timed rise from floor and nine-meter walk.
RESULTS
The results showed that loss of muscular strength and motor abilities were slowed in comparison to that observed in the natural evolution of the disease according to the literature.
CONCLUSION
We conclude that a swift and objective assessment may be performed using the MRC scale for lower limbs and trunk, the Hammersmith motor ability score, timed nine-meter walk and weight lifts.
目的
应用一种评估方案来量化和描述32例年龄在5至12岁且正在接受类固醇治疗的杜氏肌营养不良症（DMD）患者的肌肉力量和运动能力。
方法
在最初的六个月每月进行评估，此后每两个月进行一次评估，直至14个月的终点。所采用的测试包括：医学研究委员会（MRC）量表；哈默史密斯运动能力评分；最大举重重量；从地面定时起身和九米步行。
结果
结果表明，与文献中报道的该疾病自然进展过程中观察到的情况相比，肌肉力量和运动能力的丧失有所减缓。
结论
我们得出结论，使用MRC下肢和躯干量表、哈默史密斯运动能力评分、定时九米步行和举重可以进行快速且客观的评估。
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