[菘蓝根化学成分的研究]

[Studies on chemical constituents in root of Isatis indigotica].

作者信息

Zuo Li, Li Jian-bei, Xu Jing, Yang Jing-zhi, Zhang Dong-ming, Tong Yong-ling

机构信息

Institute of Materia Medica, CAMS & PUMC, Beijing 100050, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2007 Apr;32(8):688-91.

PMID:17608220

Abstract

OBJECTIVE

To study the chemical constituents in the root of Isatis indigotica.

METHOD

The constituents root were separated through various chromatographic techniques and their structures were elucidated by means of physicochemical properties and the analysis of their spectral data.

RESULT

Eleven compounds were isolated and identified as (+) -isolariciresinol (1), lariciresinol (2), lariciresinol-9-O-beta-D-glucopyranoside (3), lariciresinol-4'-O-beta-D-glucopyranoside (4), lariciresinol-4,4'-bis-O-beta-D-glucopyranoside (5), 3-formylindole (6), 1-methoxy-3-indolecarbaldehyde (7), 1-methoxy-3-indoleacetonitrile (8), deoxyvasicinone (9), epigoitrin (10), adenosine (11).

CONCLUSION

Compounds 4-8 were isolated from I. indigotica for the first time.

摘要

目的

研究菘蓝根中的化学成分。

方法

通过各种色谱技术对菘蓝根中的成分进行分离，并借助理化性质和光谱数据分析阐明其结构。

结果

分离并鉴定出11种化合物，分别为(+) -异落叶松脂醇(1)、落叶松脂醇(2)、落叶松脂醇-9-O-β-D-吡喃葡萄糖苷(3)、落叶松脂醇-4'-O-β-D-吡喃葡萄糖苷(4)、落叶松脂醇-4,4'-双-O-β-D-吡喃葡萄糖苷(5)、3-甲酰基吲哚(6)、1-甲氧基-3-吲哚甲醛(7)、1-甲氧基-3-吲哚乙腈(8)、去氧瓦西酮(9)、表告依春(10)、腺苷(11)。