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[从四倍体板蓝根中分离得到的一种新生物碱]

[A new alkaloids isolated from tetraploidy banlangen].

作者信息

Li Bin, Chen Wang-sheng, Zhang Han-ming, Zhang Wei-dong, Yang Gen-jin, Qiao Chuan-zhuo

机构信息

College of Pharmacy, Second Military Medical University, Shanghai 200433, China.

出版信息

Yao Xue Xue Bao. 2003 Jun;38(6):430-2.

PMID:14513802
Abstract

AIM

To investigate the chemical constituents of tetraploidy Banlangen (Isatis indigotica Fort.).

METHODS

Compounds were separated by chromatography on silica gel. Their structures were determined by spectral analysis and chemical evidence.

RESULTS

Three compounds were isolated. Their structures were identified as (E)-2-[(3'-indole) cyanomethylene]-3-indolinone (I), 2-(4-hydroxy-3-methoxyphenyl)-4-[(4-hydroxy-3-methoxy-phenyl)-methyl]-3- hydroxymethyl-tetrahydro-furan (II) and 2-methoxy-4-[tetrahydro-4-[(4-hydroxy-3-methoxy-phenyl)-methyl]-3- hydroxymethyl-2-furanyl] phenyl-1-O-beta-D-glucopyranoside (III).

CONCLUSION

Compound I is a new compound.

摘要

目的

研究四倍体板蓝根(菘蓝)的化学成分。

方法

采用硅胶柱色谱法分离化合物。通过光谱分析和化学证据确定其结构。

结果

分离得到3个化合物。其结构分别鉴定为(E)-2-[(3'-吲哚)氰基亚甲基]-3-吲哚酮(I)、2-(4-羟基-3-甲氧基苯基)-4-[(4-羟基-3-甲氧基苯基)-甲基]-3-羟甲基-四氢呋喃(II)和2-甲氧基-4-[四氢-4-[(4-羟基-3-甲氧基苯基)-甲基]-3-羟甲基-2-呋喃基]苯基-1-O-β-D-吡喃葡萄糖苷(III)。

结论

化合物I为新化合物。

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