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[注意缺陷多动障碍和自闭症中神经心理表现特征的年龄依赖性差异]

[Age-dependent differences in neuropsychological performance profiles in ADHD and autism].

作者信息

Sinzig Judith, Bruning Nicole, Morsch Dagmar, Lehmkuhl Gerd

机构信息

Klinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters, Universität Kö1n.

出版信息

Z Kinder Jugendpsychiatr Psychother. 2007 Mar;35(2):95-104; quiz 105-6. doi: 10.1024/1422-4917.35.2.95.

DOI:10.1024/1422-4917.35.2.95
PMID:17608279
Abstract

OBJECTIVES

Children and adolescents with autism or with attention deficit-hyperactivity disorder (ADHD) are compared in this study to three different age groups of healthy children and adolescents normally developed in terms of the severity of neuropsychological variables.

METHODS

42 children with autism and 31 children with ADHD according to DSM-IV as well as 30 healthy controls were assessed consecutively. Neuropsychological attention tasks (sustained attention, inhibition and setshifting) and executive functioning tasks (working memory and planning) were performed. Facial affect recognition ws assessed with a computer-based program to teach emotion processing using full faces and selected eye-pairs.

RESULTS

Our data provide evidence that the attention functions we studied seem to improve with age. Differences between the two clinical groups are found particularly among the 11- to 14-year-olds in the domains of sustained attention and inhibition. We detected no statistically significant differences among the three age groups in either the domain of executive functions or in the domain of facial affect recognition.

CONCLUSIONS

Although our results can only be interpreted with caution because of the descriptive character of the study and the small sample size, it nonetheless seems to be reasonable to take into account age as a relevant aspect in the utilisation of neuropsychological test procedures to better master the individual performance of different patient groups.

摘要

目的

本研究将患有自闭症或注意力缺陷多动障碍(ADHD)的儿童和青少年与正常发育的三个不同年龄组的健康儿童和青少年在神经心理学变量严重程度方面进行比较。

方法

连续评估了42名根据《精神疾病诊断与统计手册》第四版(DSM-IV)诊断为自闭症的儿童、31名诊断为ADHD的儿童以及30名健康对照者。进行了神经心理学注意力任务(持续注意力、抑制和转换任务)和执行功能任务(工作记忆和计划)。使用基于计算机的程序评估面部表情识别,该程序通过完整面部和选定的眼部配对来教授情绪处理。

结果

我们的数据表明,我们研究的注意力功能似乎随着年龄的增长而改善。两个临床组之间的差异尤其在11至14岁的儿童中出现在持续注意力和抑制领域。我们在执行功能领域或面部表情识别领域未发现三个年龄组之间存在统计学上的显著差异。

结论

尽管由于本研究的描述性性质和样本量较小,我们的结果只能谨慎解释,但在使用神经心理学测试程序时将年龄作为一个相关因素考虑在内,以更好地掌握不同患者群体的个体表现,似乎是合理的。

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引用本文的文献

1
[Autism and ADHD across the life span. Differential diagnoses or comorbidity?].[自闭症与注意力缺陷多动障碍的终生发展。鉴别诊断还是共病?]
Nervenarzt. 2011 May;82(5):573-80. doi: 10.1007/s00115-010-3239-6.
2
Differential diagnosis of autism spectrum disorder and attention deficit hyperactivity disorder by means of inhibitory control and 'theory of mind'.通过抑制控制和“心理理论”对自闭症谱系障碍和注意缺陷多动障碍进行鉴别诊断。
J Autism Dev Disord. 2011 Dec;41(12):1718-26. doi: 10.1007/s10803-011-1205-1.