Jürimäe Jaak, Jürimäe Toivo, Purge Priit
Institute of Sport Pedagogy and Coaching Sciences, Centre of Behavioral and Health Sciences, University of Tartu, Tartu, Estonia.
Exp Biol Med (Maywood). 2007 Jul;232(7):904-9.
The aim of the present investigation was to investigate plasma ghrelin response to acute maximal exercise in elite male rowers. Eight elite male rowers performed a maximal 6000-m rowing ergometer test (mean performance time: 19 mins 52 secs; 1192.1 +/- 16.4 secs), and venous blood samples were obtained before, immediately after, and after 30 mins of recovery. In addition to ghrelin concentration, leptin, insulin, growth hormone, insulin-like growth factor-1 (IGF-1), testosterone, cortisol, and glucose values were measured. Ghrelin was significantly increased immediately after the exercise (+24.4%; P < 0.05) and was not significantly different than baseline after 30 mins of recovery. Leptin was significantly decreased immediately after the exercise (- 15.8%; P < 0.05) and remained significantly decreased after the first 30 mins of recovery. No changes occurred in insulin concentrations. Growth hormone, IGF-1, and testosterone values were significantly increased and decreased to the pre-exercise level immediately after the exercise and after the first 30 mins of recovery, respectively. Cortisol and glucose values were significantly increased immediately after the exercise and remained significantly increased during the first 30 mins of recovery. There were no relationships between plasma ghrelin and other measured blood parameters after the exercise, nor were changes in ghrelin related to changes in other measured blood biochemical values after the exercise. In conclusion, these results suggest that acute negative energy balance induced by specific maximal short-term exercise elicits a metabolic response with opposite changes in ghrelin and leptin concentrations in elite male athletes.
本研究的目的是调查精英男性赛艇运动员血浆胃饥饿素对急性最大运动的反应。八名精英男性赛艇运动员进行了6000米的最大划船测力计测试（平均成绩时间：19分52秒；1192.1±16.4秒），并在运动前、运动后即刻以及恢复30分钟后采集静脉血样。除了测量胃饥饿素浓度外，还测量了瘦素、胰岛素、生长激素、胰岛素样生长因子-1（IGF-1）、睾酮、皮质醇和葡萄糖值。运动后即刻胃饥饿素显著增加（+24.4%；P<0.05），恢复30分钟后与基线无显著差异。运动后即刻瘦素显著降低（-15.8%；P<0.05），在恢复的前30分钟内仍显著降低。胰岛素浓度无变化。生长激素、IGF-1和睾酮值在运动后即刻显著增加，分别在运动后和恢复的前30分钟后降至运动前水平。运动后即刻皮质醇和葡萄糖值显著增加，在恢复的前30分钟内仍显著升高。运动后血浆胃饥饿素与其他测量的血液参数之间无相关性,运动后胃饥饿素的变化也与其他测量的血液生化值的变化无关。总之，这些结果表明，特定的最大短期运动诱导的急性负能量平衡在精英男性运动员中引发了一种代谢反应，胃饥饿素和瘦素浓度发生相反变化。
