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[疑似急性阑尾炎的超声诊断:手术的可能或确定指征?]

[Ultrasonic diagnosis in suspected acute appendicitis: probable or certain indications for surgery?].

作者信息

Zielke A, Malewski U, Lindlar R, Förster R, Klotter H J, Rüschoff J, Sitter H, Rothmund M

机构信息

Klinik für Allgemeinchirurgie, Philipps-Universität Marburg.

出版信息

Chirurg. 1991 Oct;62(10):743-9.

PMID:1760954
Abstract

The diagnostic accuracy and the clinical impact of routine ultrasonography performed by 4 surgeons, were prospectively studied in 366 unselected patients admitted for suspected acute appendicitis. Clinical and sonographic findings on admission were correlated with laparotomy findings, pathological outcome and clinical as well as follow-up data. The overall sensitivity, specificity and accuracy of the clinical diagnosis of acute appendicitis were 55.3%, 94.6% and 84.2% respectively (positive predictive value (PPV) 75.8%, negative predictive value (NPV) 87.3%). Ultrasound enabled visualization of the disease in 67 of 85 (prevalence 23.3%) patients with a histologically confirmed acute appendicitis; false positive results were recorded in 7 cases (sensitivity 78.8%, specificity 97.5%, accuracy 93.1%, PPV 90.5%, NPV 93.8%). Ultrasound was particularly useful in patients presenting with equivocal or highly unsuspective signs of acute appendicitis: of 38 patients with an acute appendicitis in this group ultrasonography enabled to make the diagnosis in 26. The combined approach of clinical evaluation and routine ultrasonography markedly improved the diagnostic accuracy (sensitivity 85.9%, specificity 96.4%, accuracy 94%) and substantially reduced the negative laparotomy rate (7.9%) in patients with suspected acute appendicitis. It is concluded, that ultrasonographic evaluation of the patient with suspected acute appendicitis performed by surgeons is of great assistance in surgical practice.

摘要

前瞻性研究了4名外科医生对366例因疑似急性阑尾炎入院的未经过筛选的患者进行常规超声检查的诊断准确性和临床影响。将入院时的临床和超声检查结果与剖腹手术结果、病理结果以及临床和随访数据进行关联。急性阑尾炎临床诊断的总体敏感性、特异性和准确性分别为55.3%、94.6%和84.2%(阳性预测值(PPV)为75.8%,阴性预测值(NPV)为87.3%)。在85例(患病率23.3%)经组织学确诊为急性阑尾炎的患者中,超声检查使其中67例患者的病情得以可视化;记录到7例假阳性结果(敏感性78.8%,特异性97.5%,准确性93.1%,PPV 90.5%,NPV 93.8%)。超声检查在表现为急性阑尾炎症状不明确或高度可疑的患者中特别有用:在该组38例急性阑尾炎患者中,超声检查使其中26例得以确诊。临床评估和常规超声检查相结合的方法显著提高了诊断准确性(敏感性85.9%,特异性96.4%,准确性94%),并大幅降低了疑似急性阑尾炎患者的阴性剖腹手术率(7.9%)。得出结论,外科医生对疑似急性阑尾炎患者进行超声检查评估在外科实践中有很大帮助。

引用本文的文献

1
[Acute appendicitis. Modern diagnostics--surgical ultrasound].
Chirurg. 2009 Jul;80(7):579-87. doi: 10.1007/s00104-009-1684-1.
2
Diagnostic score in appendicitis. Validation of a diagnostic score (Eskelinen score) in patients in whom acute appendicitis is suspected.
Langenbecks Arch Surg. 2004 Jun;389(3):213-8. doi: 10.1007/s00423-003-0436-9. Epub 2003 Nov 18.
3
[Clinical standardization in acute abdominal pain].
Langenbecks Arch Chir. 1996;381(2):65-74. doi: 10.1007/BF00183935.
4
Ultrasound scanning of the acute abdomen by surgeons in training.
Ann R Coll Surg Engl. 1994 Jul;76(4):228-33.
5
[Ultrasound diagnosis of appendicitis by surgeons--a matter of experience? A prospective study].
Langenbecks Arch Chir. 1994;379(6):335-40. doi: 10.1007/BF00191579.

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