Dobie Robert A
University of California Davis, Sacramento, CA, USA.
Ear Hear. 2007 Aug;28(4):580-91. doi: 10.1097/AUD.0b013e31806dc286.
To (1) estimate noise-induced permanent threshold shift (NIPTS) values from the data of the 1968-1972 Occupational Noise and Hearing Survey (ONHS); (2) compare these NIPTS estimates to NIPTS predictions from an international standard (ISO-1999); (3) determine why excess risk estimates based on the ONHS are so much higher than those based on ISO-1999.
The ONHS raw data were acquired from the National Institute for Occupational Safety and Health. Binaural average thresholds from 0.5 to 6 kHz were calculated for each of 1291 noise-exposed subjects (80 to 94 dBA, for up to 30 yr, all tested just before their shifts) and 665 non-noise-exposed control subjects (mostly office workers, tested throughout the work day). "Screened" subjects had had no prior significant noise exposure and had no evidence of other ear disease, whereas "excluded" subjects had failed one or more screening criteria. Twenty exposure groups were created (based on exposure level, exposure duration, and screened versus excluded status) and compared with 20 age-matched control groups. The median difference statistic estimated median NIPTS.
Median NIPTS estimates in the 3 to 6 kHz region were generally consistent with the NIPTS predictions of ISO-1999. At lower frequencies, especially at 0.5 and 1 kHz, the ONHS estimates were significantly larger than the ISO-1999 predictions, even for exposures below 90 dBA, but these differences did not increase systematically with exposure level and duration.
High-frequency median NIPTS estimates from ONHS data are consistent with the predictions of ISO-1999. Differences between exposed and control low-frequency thresholds in the ONHS are higher than predicted by ISO-1999, but these differences probably are related more to socioeconomic or test procedure effects than to occupational noise exposure. These low-frequency effects explain why excess risk estimates from the ONHS are higher than those based on ISO-1999.
(1)根据1968 - 1972年职业噪声与听力调查(ONHS)的数据估算噪声诱发的永久性阈移(NIPTS)值;(2)将这些NIPTS估算值与国际标准(ISO - 1999)的NIPTS预测值进行比较;(3)确定为何基于ONHS的超额风险估算值远高于基于ISO - 1999的估算值。
ONHS原始数据取自美国国家职业安全与健康研究所。为1291名噪声暴露受试者(80至94分贝A声级,暴露长达30年,均在轮班前接受测试)和665名非噪声暴露对照受试者(主要是办公室工作人员,在整个工作日接受测试)计算了0.5至6千赫兹的双耳平均听阈。“筛选合格”的受试者既往无显著噪声暴露史且无其他耳部疾病证据,而“排除”的受试者未通过一项或多项筛选标准。创建了20个暴露组(基于暴露水平、暴露持续时间以及筛选合格与排除状态),并与20个年龄匹配的对照组进行比较。中位数差异统计量估算了NIPTS中位数。
在3至6千赫兹区域,NIPTS中位数估算值总体上与ISO - 1999的NIPTS预测值一致。在较低频率,尤其是0.5和1千赫兹时,即使对于低于90分贝A声级的暴露,ONHS估算值也显著大于ISO - 1999的预测值,但这些差异并未随暴露水平和持续时间系统性增加。
来自ONHS数据的高频NIPTS中位数估算值与ISO - 1999的预测值一致。ONHS中暴露组与对照组低频听阈的差异高于ISO - 1999的预测值,但这些差异可能更多与社会经济或测试程序效应有关,而非职业噪声暴露。这些低频效应解释了为何基于ONHS的超额风险估算值高于基于ISO - 1999的估算值。