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Partial HELLP syndrome in pregnancy complicated by recurrent deep vein thromboses and palmar skin lesions in a patient with prothrombin gene 20210a mutation and antiphospholipid antibodies: an unusual case.

作者信息

Asherson Ronald A, Spargo Cathy, Gómez-Puerta Jose A

机构信息

Division of Immunology, School of Pathology, University of the Witwatersrand School of Medicine, Johannesburg, South Africa.

出版信息

Clin Rheumatol. 2008 Feb;27(2):245-8. doi: 10.1007/s10067-007-0683-1. Epub 2007 Jul 3.

Abstract

A patient who developed thrombocytopenia and hypertension accompanied by high levels of antiphospholipid antibodies and abnormal liver function tests in the absence of a hemolytic anemia necessitating termination of pregnancy developed bilateral lower limb thromboses accompanied by painful maculo papular lesions on the palms of both hands a few days after ending the pregnancy. She was then also found to have a prothrombin gene G20210A mutation. She was treated with anticoagulation therapy, but her postpartum course was further complicated by pulmonary embolus. A Greenfield filter was inserted into the inferior vena cava. On low molecular weight heparin, her next pregnancy was uneventful and without any complications.

摘要

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