Bassotti G, Bucaneve G, Betti C, Patoia L, Baratta E, Maresca V, Pelli M A, Morelli A, Del Favero A
Istituto di Gastroenterologia ed Endoscopia Digestiva, Universita di Perugia, Italy.
Eur J Clin Pharmacol. 1991;41(5):497-500. doi: 10.1007/BF00626379.
In experimental animal models nonsteroidal anti-inflammatory drugs may influence gastrointestinal motility, but as evidence is lacking in man. The effect of diclofenac sodium 75 mg i.m. on the motor response of the upper gastrointestinal tract to food has been studied by manometry in 9 healthy volunteers. Diclofenac had no effect on the motor activity of the stomach, duodenum, or jejunum after a 605 kcal meal.
在实验动物模型中，非甾体抗炎药可能会影响胃肠蠕动，但在人类中缺乏相关证据。通过测压法对9名健康志愿者进行研究，观察了75毫克双氯芬酸钠肌肉注射对人上消化道对食物的运动反应的影响。在摄入605千卡的食物后，双氯芬酸对胃、十二指肠或空肠的运动活性没有影响。
