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[胎儿颅内恶性畸胎瘤的产前诊断]

[Prenatal diagnosis of malignant intracranial teratoma in the fetus].

作者信息

Eckmann C, Hüneke B, Schlotfeldt T C, Carstensen M H, Reinhold S

机构信息

Frauenklinik, Universitäts-Krankenhaus Eppendorf, Hamburg.

出版信息

Geburtshilfe Frauenheilkd. 1991 Oct;51(10):859-60. doi: 10.1055/s-2008-1026226.

Abstract

At 24 weeks of gestation, an intracranial cystic lesion of 3 cm diameter, without further associated foetal malformations, was detected by ultrasound in a 25-year old nullipara prima gravida, during routine prenatal care. Within 5 weeks, the cystic mass developed into a predominantly solid tumour located at the 3rd ventricle, showing patterns of a rapidly growing malignant intracerebral process. At 29 weeks of gestation, pregnancy was terminated by sectio parva because of a progressive hydrocephalus with a biparietal diameter of 10.2 cm. Autopsy confirmed a malignant teratoma. Foetal intracranial teratomas are rare. Diagnosis and therapy should be carried out in perinatal centres.

摘要

在妊娠24周时,一名25岁未产妇初孕妇在常规产前检查中经超声检查发现直径3厘米的颅内囊性病变,未伴有其他胎儿畸形。5周内,囊性肿块发展为主要位于第三脑室的实性肿瘤,呈现出快速生长的恶性脑内病变特征。妊娠29周时,因进行性脑积水,双顶径达10.2厘米,行剖宫产终止妊娠。尸检证实为恶性畸胎瘤。胎儿颅内畸胎瘤罕见。诊断和治疗应在围产期中心进行。

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