Pichiecchio A, Bergamaschi R, Tavazzi E, Romani A, Todeschini A, Bastianello S
Neuroradiology Unit, Neurological Institute IRCCS Fondazione C. Mondino, 27100 Pavia, Italy.
Mult Scler. 2007 Jul;13(6):814-6. doi: 10.1177/1352458506075261. Epub 2007 Mar 15.
We report on clinical and instrumental findings of a multiple sclerosis (MS) patient with sudden right trigeminal neuralgia (TN). Magnetic resonance imaging (MRI), performed at TN onset, showed enlargement of both trigeminal nerves (TrN) at the root entry zone, with gadolinium enhancement of the cisternal portion. This is the first description of clinical and MRI findings indicative of peripheral involvement of the fifth cranial nerve in a MS patient complaining of TN. Our report shows the concomitant involvement of central and peripheral myelin in MS, and adds further highlights to the question regarding peripheral nerve involvement abnormalities associated with a disease considered limited to the central nervous system (CNS).
我们报告了一名患有突发性右三叉神经痛（TN）的多发性硬化症（MS）患者的临床及影像学检查结果。在三叉神经痛发作时进行的磁共振成像（MRI）显示，在神经根入区双侧三叉神经（TrN）增粗，脑池段有钆增强。这是首次对一名主诉三叉神经痛的MS患者中提示第五颅神经周围受累的临床及MRI表现进行描述。我们的报告显示了MS中中枢和周围髓鞘的同时受累，并进一步凸显了与一种被认为局限于中枢神经系统（CNS）的疾病相关的周围神经受累异常问题。
