食物过敏作为成人哮喘发病的一个风险因素。
Food allergy as a risk factor for asthma morbidity in adults.
作者信息
Berns Stephen H, Halm Ethan A, Sampson Hugh A, Sicherer Scott H, Busse Paula J, Wisnivesky Juan P
机构信息
Division of General Internal Medicine, Mount Sinai School of Medicine, New York, NY, USA.
出版信息
J Asthma. 2007 Jun;44(5):377-81. doi: 10.1080/02770900701364031.
BACKGROUND
The objective of this study was to evaluate the relationship between food allergy and asthma morbidity in adults.
METHODS
We interviewed a cohort of persistent asthmatics from an inner-city clinic. Allergies to food were assessed by patient report of convincing symptoms of acute allergic reactions. Outcome variables included health resource utilization and medication use.
RESULTS
The prevalence of allergy to fish, peanut, tree-nut, shellfish, and seed allergies were 3%, 3%, 3%, 13%, and 1%. Patients with allergies to > 1 food had increased asthma hospitalizations, ED visits, and use of oral steroids (p < 0.05 for all comparisons). Specifically, allergy to fish was associated with a greater risk of health resource utilization and increased frequency of oral steroid use (p < or = 0.03 for all comparisons).
CONCLUSIONS
Self-reported allergy to foods was associated with worse outcomes, suggesting that food allergy may be a risk factor for increased asthma morbidity in adults.
背景
本研究的目的是评估成人食物过敏与哮喘发病率之间的关系。
方法
我们对一家市中心诊所的一组持续性哮喘患者进行了访谈。通过患者报告的急性过敏反应的确切症状来评估食物过敏情况。结果变量包括卫生资源利用和药物使用情况。
结果
对鱼、花生、坚果、贝类和种子过敏的患病率分别为3%、3%、3%、13%和1%。对一种以上食物过敏的患者哮喘住院、急诊就诊次数及口服类固醇药物的使用均增加（所有比较的p<0.05）。具体而言，对鱼过敏与更高的卫生资源利用风险及口服类固醇药物使用频率增加相关（所有比较的p≤0.03）。
结论
自我报告的食物过敏与更差的结果相关，提示食物过敏可能是成人哮喘发病率增加的一个危险因素。
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