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藻类与原生动物培养物保藏中心(CCAP):原生生物基因组学的生物资源。

The Culture Collection of Algae and Protozoa (CCAP): a biological resource for protistan genomics.

作者信息

Gachon Claire M M, Day John G, Campbell Christine N, Pröschold Thomas, Saxon Rachel J, Küpper Frithjof C

机构信息

Scottish Association for Marine Science, Dunstaffnage Marine Laboratory, Dunbeg by Oban, Argyll, PA37 1QA, Scotland, UK.

出版信息

Gene. 2007 Dec 30;406(1-2):51-7. doi: 10.1016/j.gene.2007.05.018. Epub 2007 Jun 7.

Abstract

CCAP, the largest European protistan culture collection, is based at the Scottish Association for Marine Science near Oban, Scotland (http://www.ccap.ac.uk). The Collection comprises more than 2700 strains in the public domain, of which 1050 are marine algae, 1300 freshwater algae, and 350 protozoa. The primary mission of CCAP is to maintain and distribute defined cultures and their associated information to its customers. It also has a support and advisory function on all aspects of protistan science. In addition, it is involved in the training of students and researchers in algal identification and culture techniques. In light of the increasing number of fully sequenced protists, the CCAP is striving to provide targeted services and support to workers involved in all aspects of genomic research. At present, the Collection holds several hundred strains of genomic model taxa including: Acanthamoeba, Cafeteria, Cercomonas, Chlamydomonas, Chlorella, Cyanophora, Dictyostelium, Dunaliella, Ectocarpus, Emiliania, Euglena, Micromonas, Naegleria, Nephroselmis, Paramecium, Pavlova, Phaeodactylum, Porphyra, Pseudendoclonium, Pylaiella, Rhodomonas, Scenedesmus, Staurastrum, Tetrahymena, Thalassiosira, Volvox and Zygnema. These strains provide a defined representation of natural variation within model organisms, an increasingly useful resource for post-genomics approaches. Our aim over the next 2-5 years is to add value to the Collection by increasing the number of genome model species, and by offering an integrated, up-to-date, easy-to-use resource that would provide curated information on our strain holdings. In collaboration with other major Biological Resource Centres worldwide, we intend to build a hub providing access to both protistan cultures and their associated bioinformatics data.

摘要

CCAP是欧洲最大的原生生物培养物保藏中心,位于苏格兰奥本附近的苏格兰海洋科学协会(http://www.ccap.ac.uk)。该保藏中心拥有2700多种公开领域的菌株,其中1050种是海洋藻类,1300种是淡水藻类,350种是原生动物。CCAP的主要任务是维护并向客户分发特定的培养物及其相关信息。它还在原生生物科学的各个方面发挥支持和咨询作用。此外,它参与藻类鉴定和培养技术方面的学生及研究人员培训。鉴于已完成全基因组测序的原生生物数量不断增加,CCAP正努力为参与基因组研究各个方面的工作人员提供有针对性的服务和支持。目前,该保藏中心拥有数百种基因组模式分类单元的菌株,包括:棘阿米巴属、食菌虫属、尾滴虫属、衣藻属、小球藻属、蓝载藻属、盘基网柄菌属、杜氏藻属、海带属、裸藻属、微拟球藻属、纳格里属、肾形藻属、草履虫属、帕夫洛娃属、三角褐指藻属、紫菜属、假内孢藻属、褐管藻属、红胞藻属、栅藻属、十字藻属、四膜虫属、硅藻属、团藻属和双星藻属。这些菌株代表了模式生物自然变异的特定样本,对于后基因组学方法而言是日益有用的资源。我们未来2至5年的目标是,通过增加基因组模式物种的数量,以及提供一个整合的、最新的、易于使用的资源,为该保藏中心增值,该资源将提供有关我们所保存菌株的整理信息。我们打算与全球其他主要生物资源中心合作,建立一个枢纽,提供对原生生物培养物及其相关生物信息学数据的访问。

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