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引用本文的文献

1
Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review.超声与松质骨相互作用的机制：综述。
IEEE Trans Ultrason Ferroelectr Freq Control. 2020 Mar;67(3):454-482. doi: 10.1109/TUFFC.2019.2947755. Epub 2019 Oct 16.
2
Relationships of quantitative ultrasound parameters with cancellous bone microstructure in human calcaneus in vitro.体外人跟骨松质骨微观结构的定量超声参数关系。
J Acoust Soc Am. 2012 Feb;131(2):1605-12. doi: 10.1121/1.3672701.
3
A method for improved standardization of in vivo calcaneal time-domain speed-of-sound measurements.一种改进体内跟骨时域声速测量标准化的方法。
IEEE Trans Ultrason Ferroelectr Freq Control. 2008 Jul;55(7):1473-9. doi: 10.1109/TUFFC.2008.822.

本文引用的文献

1
Velocity dispersion of acoustic waves in cancellous bone.松质骨中声波的速度色散
IEEE Trans Ultrason Ferroelectr Freq Control. 1998;45(3):581-92. doi: 10.1109/58.677603.
2
The effects of frequency-dependent attenuation and dispersion on sound speed measurements: applications in human trabecular bone.频率依赖性衰减和频散对声速测量的影响：在人松质骨中的应用
IEEE Trans Ultrason Ferroelectr Freq Control. 2000;47(1):265-73. doi: 10.1109/58.818770.
3
Bone surface topology mapping and its role in trabecular bone quality assessment using scanning confocal ultrasound.骨表面拓扑映射及其在使用扫描共聚焦超声评估小梁骨质量中的作用。
Osteoporos Int. 2007 Jul;18(7):905-13. doi: 10.1007/s00198-007-0324-1. Epub 2007 Mar 15.
4
Quantitative Ultrasound--it is time to focus research efforts.定量超声——是时候集中研究精力了。
Bone. 2007 Jan;40(1):9-13. doi: 10.1016/j.bone.2006.07.014. Epub 2006 Sep 1.
5
Prediction of hip fracture risk by quantitative ultrasound in more than 7000 Swiss women > or =70 years of age: comparison of three technologically different bone ultrasound devices in the SEMOF study.7000多名70岁及以上瑞士女性中通过定量超声预测髋部骨折风险：SEMOF研究中三种技术不同的骨超声设备的比较
J Bone Miner Res. 2006 Sep;21(9):1457-63. doi: 10.1359/jbmr.060615.
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Distribution of longitudinal wave properties in bovine cortical bone in vitro.牛皮质骨纵向波特性的体外分布
Ultrasonics. 2006 Dec 22;44 Suppl 1:e233-7. doi: 10.1016/j.ultras.2006.06.055. Epub 2006 Jul 5.
7
Effects of frequency-dependent attenuation and velocity dispersion on in vitro ultrasound velocity measurements in intact human femur specimens.频率依赖性衰减和速度频散对完整人体股骨标本体外超声速度测量的影响。
IEEE Trans Ultrason Ferroelectr Freq Control. 2006 Jan;53(1):39-51. doi: 10.1109/tuffc.2006.1588390.
8
Quantitative heel ultrasound in a population-based study in Italy and its relationship with fracture history: the ESOPO study.意大利一项基于人群的研究中足跟定量超声检查及其与骨折史的关系：ESOPO研究
Osteoporos Int. 2006 Feb;17(2):237-44. doi: 10.1007/s00198-005-1985-2. Epub 2005 Sep 2.
9
In vitro speed of sound measurement at intact human femur specimens.
Ultrasound Med Biol. 2005 Jul;31(7):987-96. doi: 10.1016/j.ultrasmedbio.2005.02.015.
10
Prediction of density and mechanical properties of human trabecular bone in vitro by using ultrasound transmission and backscattering measurements at 0.2-6.7 MHz frequency range.通过在0.2 - 6.7MHz频率范围内进行超声透射和背散射测量，对人体小梁骨的密度和力学性能进行体外预测。
Phys Med Biol. 2005 Apr 21;50(8):1629-42. doi: 10.1088/0031-9155/50/8/001. Epub 2005 Mar 30.

人跟骨体外时域声速测量对中心频率、带宽和渡越时间标记的依赖性。

The dependence of time-domain speed-of-sound measurements on center frequency, bandwidth, and transit-time marker in human calcaneus in vitro.

作者信息

Wear Keith A

机构信息

U.S. Food and Drug Administration, Center for Devices and Radiological Health, HFZ-140, Rockville, Maryland 20852, USA.

出版信息

J Acoust Soc Am. 2007 Jul;122(1):636-44. doi: 10.1121/1.2735811.

DOI:10.1121/1.2735811
PMID:17614520
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6942661/
Abstract

Time-domain speed-of-sound (SOS) measurements in calcaneus are effective predictors of osteoporotic fracture risk. High attenuation and dispersion in bone, however, produce severe distortion of transmitted pulses that leads to ambiguity of time-domain SOS measurements. An equation to predict the effects of system parameters (center frequency and bandwidth), algorithm parameters (pulse arrival-time marker), and bone properties (attenuation coefficient and thickness) on time-domain SOS estimates is derived for media with attenuation that varies linearly with frequency. The equation is validated using data from a bone-mimicking phantom and from 30 human calcaneus samples in vitro. The data suggest that the effects of dispersion are small compared with the effects of frequency-dependent attenuation. The equation can be used to retroactively compensate data. System-related variations in SOS are shown to decrease as the pulse-arrival-time marker is moved toward the pulse center. Therefore, compared with other time-domain measures of SOS, group velocity exhibits the minimum system dependence.

摘要

跟骨的时域声速（SOS）测量是骨质疏松性骨折风险的有效预测指标。然而，骨中的高衰减和频散会使透射脉冲产生严重畸变，从而导致时域SOS测量结果模糊不清。针对衰减随频率线性变化的介质，推导了一个方程，用于预测系统参数（中心频率和带宽）、算法参数（脉冲到达时间标记）和骨特性（衰减系数和厚度）对时域SOS估计值的影响。该方程通过来自仿骨体模和30个人体跟骨样本的体外数据进行了验证。数据表明，与频率依赖性衰减的影响相比，频散的影响较小。该方程可用于对数据进行追溯补偿。结果显示，随着脉冲到达时间标记向脉冲中心移动，SOS中与系统相关的变化会减小。因此，与其他时域SOS测量方法相比，群速度表现出最小的系统依赖性。