Popescu Sidonia, Ghetu N, Grosu Oana, Nastasa Mihaela, Pieptu D
Department of Plastic and Reconstructive Surgery, Gr T Popa University of Medicine and Pharmacy, Iasi, Romania.
Chirurgia (Bucur). 2007 Mar-Apr;102(2):197-204.
Coverage is one of the most important issues in plastic surgery. The both acute and reconstructive surgery can often face with limited donor site availability requiring additional therapeutic options. One of the research direction developed in the last 30 years is the quest for the "artificial skin". Integra is a permanent skin substitute used in acute full thickness burns, after injuries and also in reconstructive surgery. We used it with very good results in three cases: in two patients for replacement of facial and neck burn scars and in one case for penis coverage in a traumatic degloving avulsion of perineal skin. Even the anatomic regions were demanding (cervical area, frontal area and penis) we had no Integra displacement. The skin graft take was 100% in all the cases. We had no hematoma, no infection. Follow up period is 3-8 months. A meticulous surgical technique with a good hemostasis and continuous wound care during first and second stage are mandatory for optimal esthetic and functional results. This is the first use of Integra in Romania. Experience is important for further steps are needed in coverage of patients with severe burn trauma.
皮肤覆盖是整形外科中最重要的问题之一。急症手术和重建手术常常会面临供区有限的情况，这就需要其他治疗选择。过去30年里开展的一个研究方向是寻找“人造皮肤”。Integra是一种永久性皮肤替代物，用于治疗急性全层烧伤、创伤后修复以及重建手术。我们在3例患者中使用了该产品，均取得了很好的效果：2例用于替代面部和颈部烧伤瘢痕，1例用于阴茎覆盖，该患者因创伤导致会阴皮肤脱套撕脱伤。即使是在解剖结构复杂的区域（颈部、前额部和阴茎），Integra也没有发生移位。所有病例中植皮成活率均为100%。未出现血肿和感染情况。随访期为3至8个月。为获得最佳的美学和功能效果，在一期和二期手术中采用细致的手术技巧、良好的止血措施以及持续的伤口护理是必不可少的。这是Integra在罗马尼亚的首次应用。经验对于进一步治疗严重烧伤创伤患者非常重要。
