Ghazi Bahair H, Williams Joseph K
Division of Plastic and Reconstructive Surgery, Department of Surgery, Emory University, Atlanta, GA, USA.
Ann Plast Surg. 2011 May;66(5):493-6. doi: 10.1097/SAP.0b013e318203ea4e.
The usefulness of Integra is well described in the adult reconstructive and burn literature. There is limited documentation of its utility in the pediatric plastic surgery population. We presented 8 cases referred to us for flap coverage that were treated using Integra. These cases describe difficult wounds resulting from trauma, and congenital abnormalities. The charts of all 8 cases were retrospectively reviewed. There were 5 females and 3 newborns. The average age at coverage with Integra was 4.6 years (range, 1 day-16 years). There were 4 traumatic wounds, 2 cases of cutis aplasia, 1 myelomeningocele, and 1 case of congenitally absent cranium. The average time to coverage was 8 days, and all trauma patients underwent at least 2 prior washout procedures. The average area covered was 43 cm (range, 6-100 cm). At a mean follow-up of 14.25 months (range, 9-20 months), 7 patients' wounds had healed without need for further flap coverage. Only 1 patient required a skin graft over the Integra bed. There was 1 infection resulting in total dermal matrix loss and need for local flap reconstruction. One patient developed severe hypertrophic scarring requiring surgical revision. Integra is a reliable option in pediatric reconstruction, which may save a child the morbidity of a more extensive procedure.
Integra在成人重建和烧伤文献中已有充分描述。但其在小儿整形外科人群中的应用记录有限。我们介绍了8例因皮瓣覆盖问题转诊至我院并使用Integra治疗的病例。这些病例描述了由创伤和先天性异常导致的复杂伤口。对所有8例病例的病历进行了回顾性分析。其中有5名女性和3名新生儿。使用Integra覆盖创面时的平均年龄为4.6岁(范围为1天至16岁)。有4例创伤性伤口、2例皮肤发育不全、1例脊髓脊膜膨出和1例先天性颅骨缺失。平均覆盖时间为8天,所有创伤患者至少接受过2次前期清创手术。平均覆盖面积为43平方厘米(范围为6至100平方厘米)。平均随访14.25个月(范围为9至20个月),7例患者的伤口已愈合,无需进一步进行皮瓣覆盖。只有1例患者需要在Integra基底上进行植皮。有1例发生感染,导致真皮基质完全丧失,需要进行局部皮瓣重建。1例患者出现严重增生性瘢痕,需要手术修复。Integra在小儿重建中是一种可靠的选择,可为患儿避免更广泛手术带来的并发症。