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66只猫的菌血症及分离株的抗菌药敏性(1995 - 2004年)

Bacteraemia in 66 cats and antimicrobial susceptibility of the isolates (1995-2004).

作者信息

Greiner Martina, Wolf Georg, Hartmann Katrin

机构信息

Clinic for Small Animal Medicine, Ludwig Maximilian University Munich, Veterinaerstrasse 13, 80539 Munich, Germany.

出版信息

J Feline Med Surg. 2007 Oct;9(5):404-10. doi: 10.1016/j.jfms.2007.04.004. Epub 2007 Jul 5.

Abstract

Bacterial blood culture results of 292 privately owned cats presented to the Clinic for Small Animal Medicine, Ludwig Maximilian University Munich with signs of sepsis were evaluated retrospectively. Of the blood cultures, 23% were positive. In 88%, a single bacterial species was isolated. Of all bacterial isolates, 45% were Gram-positive, 43% were Gram-negative, and 12% were obligate anaerobes. The most frequently isolated bacteria were Enterobacteriaceae, obligate anaerobic species, Staphylococcus species and Streptococcus species. Of the cats with positive blood cultures, 32% were pretreated with antibiotics. Of all bacterial isolates, 77% were susceptible to enrofloxacin, 69% to chloramphenicol, 67% to gentamicin, and 64% to amoxycillin clavulanic acid. Only enrofloxacin reached an in vitro efficacy of more than 70% against Gram-positive and more than 74% against Gram-negative bacteria.

摘要

对慕尼黑路德维希 - 马克西米利安大学小动物医学诊所收治的292只出现败血症症状的家养猫的细菌血培养结果进行了回顾性评估。血培养中,23%呈阳性。88%的血培养分离出单一细菌种类。在所有分离出的细菌中,45%为革兰氏阳性菌,43%为革兰氏阴性菌,12%为专性厌氧菌。最常分离出的细菌是肠杆菌科细菌、专性厌氧菌、葡萄球菌属和链球菌属。血培养呈阳性的猫中,32%曾接受过抗生素预处理。在所有分离出的细菌中,77%对恩诺沙星敏感,69%对氯霉素敏感,67%对庆大霉素敏感,64%对阿莫西林克拉维酸敏感。只有恩诺沙星对革兰氏阳性菌的体外疗效超过70%,对革兰氏阴性菌超过74%。

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