Hu J R, Nakasima A, Takahama Y
Department of Orthodontics, Faculty of Dentistry, Kyushu University, Fukuoka, Japan.
J Craniofac Genet Dev Biol. 1991 Jul-Sep;11(3):165-9.
The purposes of this study were to estimate the heritabilities of several human dental arch dimensions and compare the hereditary differences among kinships and among variables. The sample consisted of 102 Japanese families, each including both parents and one of their offspring, and on average all subjects had relatively well-aligned permanent dentitions. The heritabilities of all variables were estimated from the regression of offspring on parent and on midparent. Results showed that genetics played a role regarding dental arch dimensions, and arch perimeter (sum of tooth width) was a more definite genetic-related factor than other arch dimensions, such as width, length, or size. There were few significant hereditary differences between sons and daughters, and between upper and lower arches for each variable. Sex chromosomal involvement was not confirmed, but maternal effects were found to be more evident in daughters than in sons, for both arches. Comparisons among the heritabilities of overall and of anterior arch dimensions indicated that size of the anterior part of the dental arch might be less resistant to environmental factors, especially in case of the lower arch.
本研究的目的是估计几个人类牙弓尺寸的遗传力，并比较亲属关系之间以及变量之间的遗传差异。样本由102个日本家庭组成，每个家庭包括父母双方及其一个后代，平均而言，所有受试者的恒牙列排列相对整齐。所有变量的遗传力是通过后代对父母及中亲的回归来估计的。结果表明，遗传学在牙弓尺寸方面发挥了作用，牙弓周长（牙宽度总和）比其他牙弓尺寸（如宽度、长度或大小）是一个更明确的遗传相关因素。每个变量在儿子和女儿之间以及上下牙弓之间几乎没有显著的遗传差异。未证实性染色体的参与，但发现母系效应在两个牙弓中对女儿比对儿子更明显。整体牙弓尺寸和前牙弓尺寸遗传力的比较表明，牙弓前部的尺寸可能对环境因素的抵抗力较小，尤其是在下牙弓的情况下。
