Xue Junfeng, Miller Kurt W
Department of Molecular Biology, University of Wyoming, 1000 E. University Avenue, Dept. 3944, Laramie, WY 82071-3944, USA.
Appl Environ Microbiol. 2007 Sep;73(17):5648-52. doi: 10.1128/AEM.00052-07. Epub 2007 Jul 6.
The phosphotransferase system regulation domain (PRD)-containing activator, ManR, is required for glucose-controlled transcription of the mannose permease two (mpt) operon in Listeria innocua. His-871 in ManR PRD-II is needed for mpt repression in glucose-free media. His-506 in PRD-I is needed for mpt induction by glucose.
含磷酸转移酶系统调节结构域(PRD)的激活因子ManR是无害李斯特菌中甘露糖通透酶双基因(mpt)操纵子的葡萄糖控制转录所必需的。ManR PRD-II中的组氨酸871是无葡萄糖培养基中mpt阻遏所必需的。PRD-I中的组氨酸506是葡萄糖诱导mpt所必需的。