Lakhan Shaheen E
Global Neuroscience Initiative Foundation, Los Angeles, CA, USA.
Mol Neurodegener. 2007 Jul 6;2:13. doi: 10.1186/1750-1326-2-13.
John Finberg is a professor of pharmacology at the Faculty of Medicine, Technion - Israel Institute of Technology, home of Israel's two Nobel laureates. He and his colleague Prof. Moussa Youdim were instrumental in the early clinical development of the anti-Parkinson drug rasagiline, which gained UK- and EU-marketing authorization in 2005 and US FDA approval in 2006. In our interview, Finberg reflects on his clinical research to develop rasagiline as a commercial drug and its proposed pharmacological mechanisms of action. Moreover, he elucidates the current state of anti-Parkinson drug discovery and offers direction for future research.
约翰·芬伯格是以色列理工学院医学院的药理学教授,该学院是以色列两位诺贝尔奖获得者的母校。他和他的同事穆萨·尤迪姆教授在抗帕金森药物雷沙吉兰的早期临床开发中发挥了重要作用,该药物于2005年获得英国和欧盟的上市许可,并于2006年获得美国食品药品监督管理局的批准。在我们的采访中,芬伯格回顾了他将雷沙吉兰开发成商业药物的临床研究及其提出的药理作用机制。此外,他阐明了抗帕金森药物研发的现状,并为未来的研究提供了方向。