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老年恶病质的药物治疗:证据与安全性展望

Pharmacological treatment of geriatric cachexia: evidence and safety in perspective.

作者信息

Yeh Shing-Shing, Lovitt Sherri, Schuster Michael W

机构信息

Northport VAMC, Geriatric division, Northport, NY 11768, USA.

出版信息

J Am Med Dir Assoc. 2007 Jul;8(6):363-77. doi: 10.1016/j.jamda.2007.05.001.

DOI:10.1016/j.jamda.2007.05.001
PMID:17619035
Abstract

Anticachexic or antisarcopenic medications are prescribed worldwide for geriatric patients with poor appetite and associated weight loss. They represent a valuable treatment option for managing cachexia. However, the well-publicized adverse reports about these medications in acquired immunodeficiency syndrome (AIDS) and in the cancer population has led to some concern and much subsequent discussion over the safety of these medications being used in geriatric population. This review looks at the evidence in relation to the benefits and risks of these medications and discusses what we know about their use in the geriatric population.

摘要

抗恶病质或抗肌肉减少症药物在全球范围内被用于治疗食欲不佳及伴有体重减轻的老年患者。它们是管理恶病质的一种有价值的治疗选择。然而,这些药物在获得性免疫缺陷综合征(AIDS)患者和癌症患者中广为人知的不良反应报告,引发了一些担忧以及随后关于在老年人群中使用这些药物安全性的诸多讨论。这篇综述审视了与这些药物的益处和风险相关的证据,并讨论了我们对其在老年人群中使用的了解情况。

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