Edwards Kate M, Burns Victoria E, Carroll Douglas, Drayson Mark, Ring Christopher
Department of Psychiatry, University of California, San Diego, CA 92093-0804, USA.
Exerc Sport Sci Rev. 2007 Jul;35(3):150-5. doi: 10.1097/JES.0b013e3180a031bd.
Acute stress, such as a bout of exercise, is accepted to cause an array of immunologic changes. Recently, it has been proposed that acute stress activation of the innate immune system might be harnessed as an adjuvant to enhance immune responses to antigen challenge. This review develops the acute stress-induced immunoenhancement hypothesis and its possible role as a vaccine adjuvant.
急性应激,如一阵运动,被认为会引起一系列免疫变化。最近,有人提出,先天免疫系统的急性应激激活可作为一种佐剂,以增强对抗原刺激的免疫反应。本综述阐述了急性应激诱导的免疫增强假说及其作为疫苗佐剂的可能作用。