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对广岛和长崎原子弹幸存者45年研究的综述。早期进入者的染色体异常。

A review of forty-five years study of Hiroshima and Nagasaki atomic bomb survivors. Chromosome abnormality in early entrants.

作者信息

Kamada N

机构信息

Department of Hematology, Hiroshima University, Japan.

出版信息

J Radiat Res. 1991 Mar;32 Suppl:275-7. doi: 10.1269/jrr.32.supplement_275.

DOI:10.1269/jrr.32.supplement_275
PMID:1762115
Abstract

A preliminary study was performed to estimate radiation dose in 10 individuals who had entered Hiroshima city one day after the explosion and worked around the hypocenter area for a week. The numbers of cells with chromosome aberrations differed in each subject, ranging from one to 18 (median: 11 abnormalities) in 500 metaphases of lymphocytes cultured for 48 hours with Phytohemagglutinin. Five individuals had more than 1.6 percent stable type aberrations and were estimated to have been exposed to 6-13 rad. The other five individuals and the controls were estimated to be less than two rad.

摘要

一项初步研究对10名个体进行了辐射剂量估算,这些个体在爆炸一天后进入广岛市,并在爆心区域附近工作了一周。每个受试者的染色体畸变细胞数量各不相同,在经植物血凝素培养48小时的500个淋巴细胞中期相中,数量从1个到18个不等(中位数:11个异常)。5名个体的稳定型畸变超过1.6%,估计受到了6至13拉德的辐射。其他5名个体和对照组估计受到的辐射小于2拉德。

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