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强迫症患者的生活质量:强迫观念与强迫行为的不同影响。

Quality of life in obsessive-compulsive disorder: the different impact of obsessions and compulsions.

作者信息

Stengler-Wenzke Katarina, Kroll Michael, Riedel-Heller Steffi, Matschinger Herbert, Angermeyer Matthias C

机构信息

Department of Psychiatry, University of Leipzig, Leipzig, Germany.

出版信息

Psychopathology. 2007;40(5):282-9. doi: 10.1159/000104744. Epub 2007 Jun 28.

Abstract

BACKGROUND

Patients with obsessive-compulsive disorder (OCD) are troubled by repeated obsessions and/or compulsions, which seem senseless and frequently repugnant.

OBJECTIVE

The study examines the differential impact of obsessions and compulsions on the quality of life (QoL) of patients with OCD.

METHODS

Seventy-five patients (43 females, 32 males) between 21 and 62 years old with OCD (ICD 10 F42.0-F42.2) were recruited from the outpatient clinic for anxiety disorders at the Department of Psychiatry of the University of Leipzig. The severity of OCD symptoms was assessed by the Yale Brown Obsessive-Compulsive Scale (a standardized, clinician-administered scale), and depressiveness was assessed with the Beck Depression Inventory (a self-report instrument). QoL was assessed by means of the WHOQOL-BREF, a self-administered questionnaire developed by WHO.

RESULTS

Compulsions reduced patients' QoL in the WHOQOL-BREF domains 'physical well-being', 'psychological well-being' and 'environment', whereas obsessions did not have any impact on QoL ratings. Depressive symptoms were a strong predictor of poor QoL in OCD patients.

CONCLUSIONS

In order to judge the QoL of OCD patients, obsessions and compulsions have to be considered differently. Diagnosing and treating depressive symptoms is important for improving the QoL in OCD.

摘要

背景

强迫症(OCD)患者受反复出现的强迫观念和/或强迫行为困扰,这些观念和行为看似毫无意义且常常令人厌恶。

目的

本研究探讨强迫观念和强迫行为对强迫症患者生活质量(QoL)的不同影响。

方法

从莱比锡大学精神病学系焦虑症门诊招募了75名年龄在21至62岁之间的强迫症(ICD 10 F42.0 - F42.2)患者(43名女性,32名男性)。通过耶鲁布朗强迫症量表(一种标准化的、由临床医生实施的量表)评估强迫症症状的严重程度,并用贝克抑郁量表(一种自我报告工具)评估抑郁程度。生活质量通过世界卫生组织生活质量简表(WHOQOL - BREF)进行评估,这是由世界卫生组织编制的一份自我填写问卷。

结果

强迫行为降低了患者在WHOQOL - BREF量表中“身体健康”、“心理健康”和“环境”领域的生活质量,而强迫观念对生活质量评分没有任何影响。抑郁症状是强迫症患者生活质量差的一个强有力预测因素。

结论

为了判断强迫症患者的生活质量,必须对强迫观念和强迫行为加以区别考虑。诊断和治疗抑郁症状对改善强迫症患者的生活质量很重要。

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