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细菌磁性纳米颗粒的结构与性能研究

Research on the structure and performance of bacterial magnetic nanoparticles.

作者信息

Li Shuang-Yan, Zhao Feng-Mei

机构信息

Institute of Nanobiotechnology, School of Materials Science and Engineering Tianjin University, Tianjin 300072, China.

出版信息

J Biomater Appl. 2008 Mar;22(5):433-48. doi: 10.1177/0885328207079064. Epub 2007 Jul 10.

DOI:10.1177/0885328207079064
PMID:17623711
Abstract

Magnetite nanocrystals have been widely used in many fields. Recently, a new magnetite nanocrystals, called magnetosome, has been found in magnetotactic bacteria. In this article, we researched on the properties of magnetosomes in detail, such as crystalline, morphology, crystal-size distributions, vitro cytotoxicity, and magnetic properties and quantified primary amino groups on the magnetosomes membrane surface by fluorescamine assay for the first time. From the results, it was clear that magnetosomes have more potential in the biomedical applications than synthetic magnetite.

摘要

磁铁矿纳米晶体已在许多领域中得到广泛应用。最近,在趋磁细菌中发现了一种新的磁铁矿纳米晶体,称为磁小体。在本文中,我们详细研究了磁小体的性质,如晶体结构、形态、晶体尺寸分布、体外细胞毒性和磁性,并首次通过荧光胺测定法对磁小体膜表面的伯氨基进行了定量。从结果来看,很明显磁小体在生物医学应用中比合成磁铁矿具有更大的潜力。

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引用本文的文献

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Large-Scale Cultivation of Magnetotactic Bacteria and the Optimism for Sustainable and Cheap Approaches in Nanotechnology.大规模培养磁细菌及其在纳米技术中可持续和廉价方法的前景。
Mar Drugs. 2023 Jan 19;21(2):60. doi: 10.3390/md21020060.
2
Ganglioside-magnetosome complex formation enhances uptake of gangliosides by cells.神经节苷脂-磁小体复合物的形成增强了细胞对神经节苷脂的摄取。
Int J Nanomedicine. 2015 Nov 6;10:6919-30. doi: 10.2147/IJN.S92228. eCollection 2015.
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Magnetotactic bacteria as potential sources of bioproducts.趋磁细菌作为生物制品的潜在来源。
Mar Drugs. 2015 Jan 16;13(1):389-430. doi: 10.3390/md13010389.
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Magnetic bionanoparticle enhances homing of endothelial progenitor cells in mouse hindlimb ischemia.磁性生物纳米粒子增强内皮祖细胞在小鼠后肢缺血模型中的归巢。
Korean Circ J. 2012 Jun;42(6):390-6. doi: 10.4070/kcj.2012.42.6.390. Epub 2012 Jun 28.