Li Shuang-Yan, Zhao Feng-Mei
Institute of Nanobiotechnology, School of Materials Science and Engineering Tianjin University, Tianjin 300072, China.
J Biomater Appl. 2008 Mar;22(5):433-48. doi: 10.1177/0885328207079064. Epub 2007 Jul 10.
Magnetite nanocrystals have been widely used in many fields. Recently, a new magnetite nanocrystals, called magnetosome, has been found in magnetotactic bacteria. In this article, we researched on the properties of magnetosomes in detail, such as crystalline, morphology, crystal-size distributions, vitro cytotoxicity, and magnetic properties and quantified primary amino groups on the magnetosomes membrane surface by fluorescamine assay for the first time. From the results, it was clear that magnetosomes have more potential in the biomedical applications than synthetic magnetite.
磁铁矿纳米晶体已在许多领域中得到广泛应用。最近,在趋磁细菌中发现了一种新的磁铁矿纳米晶体,称为磁小体。在本文中,我们详细研究了磁小体的性质,如晶体结构、形态、晶体尺寸分布、体外细胞毒性和磁性,并首次通过荧光胺测定法对磁小体膜表面的伯氨基进行了定量。从结果来看,很明显磁小体在生物医学应用中比合成磁铁矿具有更大的潜力。