Nomelini R S, Micheletti A M R, Adad S J, Murta E F C
Research Institute of Oncology (IPON)/Discipline of Gynecology and Obstetrics, Federal University of Triângulo Mineiro (UFTM), Uberaba-MG, Brazil.
Eur J Gynaecol Oncol. 2007;28(3):236-8.
Granulosa cell tumors account for approximately 1-2% of all ovarian tumors. There are two types: adult granulosa cell tumor and juvenile granulosa cell tumor. Juvenile granulosa cell tumors constitute 5% of this histological subtype, and the prognosis is good because the majority present as Stage I tumors. The treatment can consist of conservative surgery. Androgen production is rare and produces virilization in women. These tumors are usually solid or predominantly solid. We describe the case of a 13-year-old girl with androgenic manifestations and increased abdominal size. Her plasma testosterone level was elevated. A left adnexal cyst (14.4 x 9.1 x 9.7 cm) was revealed at pelvic ultrasonography. The patient underwent an exploratory laparotomy, revealing a left ovarian cystic tumor. Diagnosis was juvenile granulosa cell tumor.
颗粒细胞瘤约占所有卵巢肿瘤的1%-2%。有两种类型:成人颗粒细胞瘤和青少年颗粒细胞瘤。青少年颗粒细胞瘤占该组织学亚型的5%,由于大多数表现为I期肿瘤,预后良好。治疗可包括保守手术。雄激素分泌罕见,会导致女性男性化。这些肿瘤通常为实性或主要为实性。我们描述了一名13岁有雄激素表现且腹部增大的女孩的病例。她的血浆睾酮水平升高。盆腔超声检查发现左附件囊肿(14.4×9.1×9.7cm)。患者接受了剖腹探查术,发现左卵巢囊性肿瘤。诊断为青少年颗粒细胞瘤。