Bourg Gisèle, O'Callaghan David, Boschiroli Maria Laura
Institut National de la Santé et de la Recherche Médicale, ESPRI 26, UFR de Médecine, CS 83021, Avenue J F Kennedy, 30908 NIMES Cedex 02, France.
Vet Microbiol. 2007 Dec 15;125(3-4):375-80. doi: 10.1016/j.vetmic.2007.06.002. Epub 2007 Jun 13.
The genomic structure and the restriction maps were studied in 24 Brucella strains isolated from marine mammals. From SpeI restriction profiles, the strains could be ascribed to three clonal groups, each corresponding to a specific host. Cross contamination between exclusively terrestrial and exclusively marine hosts is unlikely suggesting the divergence of the different species of the genus Brucella which may have taken place 60 million years ago, concomitant with the radiation of their mammalian hosts (Artiodactyla) from other mammalian orders.
对从海洋哺乳动物分离出的24株布鲁氏菌菌株的基因组结构和限制性图谱进行了研究。根据SpeI限制性酶切图谱，这些菌株可归为三个克隆群，每个克隆群对应一种特定的宿主。陆地宿主和海洋宿主之间不太可能发生交叉污染，这表明布鲁氏菌属不同物种的分化可能发生在6000万年前，与它们的哺乳动物宿主（偶蹄目）从其他哺乳动物目辐射分化的时间一致。
