Sultan N, Türet S, Imir T
Gazi Universitesi, Tip Fakültesi, Mikrobiyoloji Anabilim Dali.
Mikrobiyol Bul. 1991 Jul;25(3):227-34.
In this study, 231 Methicillin-Resistant Staphylococcus (MRS) and 76 Methicillin-Susceptible Staphylococcus (MSS) strains were investigated. 23 antibiotics were tested by using Modified Kirby-Bauer Technique. The highest resistance ration in MRS strains were found for lincomycin, clindamycin and ampicillin with the ratios of 61.0%, 59.3%, and 56.2% respectively. And the lowest resistance ratios were measured for vancomycin, ciprofloxacin and ofloxacin 0.5%, 8.2%, 10.8% respectively. It was found that, resistance of MRS strains to 17 antibiotics were significantly higher than resistance of MSS strains, but not for sulbactam-ampicillin, cefoperazone, ceftriaxone, vancomycin, ciprofloxacin, ofloxacin and netilmicin.
在本研究中，对231株耐甲氧西林葡萄球菌（MRS）和76株甲氧西林敏感葡萄球菌（MSS）进行了调查。采用改良 Kirby-Bauer 技术对23种抗生素进行了测试。MRS菌株中对林可霉素、克林霉素和氨苄西林的耐药率最高，分别为61.0%、59.3%和56.2%。而对万古霉素、环丙沙星和氧氟沙星的耐药率最低，分别为0.5%、8.2%和10.8%。结果发现，MRS菌株对17种抗生素的耐药性显著高于MSS菌株，但对舒巴坦-氨苄西林、头孢哌酮、头孢曲松、万古霉素、环丙沙星、氧氟沙星和奈替米星则不然。
