Alvarez Tamargo José A, Simarro Martín-Ambrosio Eugenio, Romero Tarín Enrique, Martín Fernández María, Hevia Nava Sergio, Barriales Alvarez Vicente, Morís de la Tassa Cesar
Unidad de Cardiología, Hospital Carmen y Severo Ochoa, Cangas del Narcea, España.
Cardiology. 2008;109(1):1-9. doi: 10.1159/000105320. Epub 2007 Jul 10.
There has been no clear consensus regarding the optimum definition of a high-risk exercise ECG test. The aim of this study is to compare the diagnostic accuracy of several treadmill scores [American College of Cardiology/American Heart Association (ACC/AHA) High-Risk Criteria for exercise testing, Duke Treadmill Score, Veterans Affairs and West Virginia Prognostic Score, ST/Heart Rate Index] with the ST-segment depression analysis in the detection of significant and severe coronary disease as determined by coronary angiography.
The study included a cohort of 248 consecutive patients admitted to hospital for unstable angina.
The sensitivities of the ACC/AHA High-Risk Criteria and the ST depression > or =1 mm were 89.02 and 76.83%, respectively, for the detection of significant coronary artery disease, and 96.15 and 86.54% for the detection of severe coronary artery disease. The specificities of the Duke Treadmill Score and the ST depression > or=1 mm were 96.43 and 73.81%, respectively, for the detection of significant coronary artery disease, and 81.63 and 47.45% for the detection of severe coronary artery disease.
The ACC/AHA High-Risk Criteria and Duke Treadmill Score provided relevant diagnostic information not available from the ST segment analysis alone.
关于高危运动心电图测试的最佳定义尚无明确共识。本研究的目的是比较几种跑步机评分[美国心脏病学会/美国心脏协会(ACC/AHA)运动试验高危标准、杜克跑步机评分、退伍军人事务部和西弗吉尼亚州预后评分、ST/心率指数]与ST段压低分析在通过冠状动脉造影确定的显著和严重冠状动脉疾病检测中的诊断准确性。
该研究纳入了连续248例因不稳定型心绞痛入院的患者。
ACC/AHA高危标准和ST段压低≥1mm检测显著冠状动脉疾病的敏感性分别为89.02%和76.83%,检测严重冠状动脉疾病的敏感性分别为96.15%和86.54%。杜克跑步机评分和ST段压低≥1mm检测显著冠状动脉疾病的特异性分别为96.43%和73.81%,检测严重冠状动脉疾病的特异性分别为81.63%和47.45%。
ACC/AHA高危标准和杜克跑步机评分提供了仅从ST段分析中无法获得的相关诊断信息。