Bharucha Diana X, Campbell Timothy B, Valencia Ignacio, Hardison H Huntley, Kothare Sanjeev V
Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Pediatr Neurol. 2007 Jul;37(1):59-63. doi: 10.1016/j.pediatrneurol.2007.03.008.
Ophthalmoplegic migraine (also recognized as a cranial neuralgia) is a form of migraine characterized by recurrent episodes of headache with ophthalmoplegia related to paresis of cranial nerves III, IV, or VI, with onset typically in childhood. These symptomatic episodes may persist for several hours or for several weeks, months, or permanently. To date, the exact etiology of ophthalmoplegic migraine remains unknown. In previous case reports, ophthalmoplegic migraine may or may not be associated with changes seen on magnetic resonance imaging. Contrast-enhanced magnetic resonance imaging performed during symptomatic and postsymptomatic periods in patients with ophthalmoplegic migraine may hold great value in identifying the pathophysiologic features of oculomotor nerve palsies. Of cases demonstrating abnormal magnetic resonance imaging, a majority show improved but persistent changes on repeat imaging. The present report describes a case of recurrent ophthalmoplegic migraine in a 16-year-old girl. Although the patient presented with ophthalmoplegic migraine during this episode in the same manner as her prior episodes, enhancement of the cranial nerve III on magnetic resonance imaging was evident during the eighth episode whereas previous imaging had been normal. Complete resolution of enhancement of the oculomotor nerve on repeat imaging adds to the few cases that have shown such findings in patients with recurrent ophthalmoplegic migraine. A review of previous reported cases of ophthalmoplegic migraine is offered.
眼肌麻痹性偏头痛（也被认为是一种颅神经痛）是偏头痛的一种形式，其特征为反复发作的头痛并伴有与动眼神经（III）、滑车神经（IV）或展神经（VI）麻痹相关的眼肌麻痹，通常起病于儿童期。这些症状性发作可能持续数小时、数周、数月或永久性存在。迄今为止，眼肌麻痹性偏头痛的确切病因仍不清楚。在既往的病例报告中，眼肌麻痹性偏头痛可能与或不与磁共振成像上所见的改变相关。在眼肌麻痹性偏头痛患者的症状期和症状后期进行的对比增强磁共振成像，对于识别动眼神经麻痹的病理生理特征可能具有重要价值。在显示磁共振成像异常的病例中，大多数在重复成像时显示改善但持续存在的改变。本报告描述了一名16岁女孩复发性眼肌麻痹性偏头痛的病例。尽管该患者在此次发作时出现的眼肌麻痹性偏头痛与之前的发作方式相同，但在第八次发作时磁共振成像显示动眼神经（III）增强，而之前的成像结果正常。重复成像时动眼神经增强完全消退，这在复发性眼肌麻痹性偏头痛患者中显示出此类发现的病例较少。本文还对既往报道的眼肌麻痹性偏头痛病例进行了综述。
