Jaffrin Michel Y, Moreno Marie Valerie
Biomechanics and Biomedical Engineering Laboratory, UMR CNRS 6600, Technological University of Compiegne, 60205 Compiegne, France.
Med Eng Phys. 2008 May;30(4):483-9. doi: 10.1016/j.medengphy.2007.05.009. Epub 2007 Jul 12.
The objective was to set-up a method for measuring total body water volumes (TBW) using a Tefal foot-to-foot impedancemeter (FFI) by comparison with a multifrequency medical impedancemeter and to validate this method against deuterium dilution data. The investigation was carried out in 57 Caucasian adult subjects. Impedancemeters were a Tefal Bodymaster Vision (foot-to-foot) featuring a square wave signal and a Xitron Hydra 4200 (5-1000 kHz) using BIS method. TBW was measured by the Xitron using a new method that we have developed which applies the BIS method directly to extra and intracellular fluids combined. Although the high frequency impedance of the FFI (R(hf)) was higher than the Xitron infinite frequency resistance and corresponded to a frequency around 100 kHz, TBW differences between the FFI and Xitron were not significant, 0.17+/-2.17 L for men (P=0.694) and 0.04+/-1.88 L for women (P=0.902). Then, our method was tested on another Caucasian population in which R(hf) had been measured with the same FFI, together with TBW measurements by deuterium dilution. TBW differences between the FFI and dilution were -0.38+/-2.27 L for men (P=0.237) and -0.72+/-2.37 L for women (P=0.06). Our method permits, at least in a Caucasian healthy population, to measure TBW using this FFI with the same accuracy as a whole body multifrequency medical impedancemeter, and the measurement, made in upright position, is much quicker.
目的是通过与多频医学阻抗仪比较,建立一种使用特福脚部对脚部阻抗仪(FFI)测量全身水体积(TBW)的方法,并根据氘稀释数据验证该方法。该研究在57名白种成年受试者中进行。阻抗仪分别是具有方波信号的特福身体大师视觉型(脚部对脚部)和使用生物电阻抗谱(BIS)方法的西特龙Hydra 4200(5 - 1000 kHz)。TBW由西特龙使用我们开发的一种新方法测量,该方法将BIS方法直接应用于细胞外液和细胞内液的组合。尽管FFI的高频阻抗(R(hf))高于西特龙的无限频率电阻,且对应频率约为100 kHz,但FFI和西特龙之间的TBW差异不显著,男性为0.17±2.17 L(P = 0.694),女性为0.04±1.88 L(P = 0.902)。然后,我们的方法在另一组白种人群中进行测试,该组人群使用同一FFI测量了R(hf),并通过氘稀释测量了TBW。FFI和稀释法之间的TBW差异男性为 - 0.38±2.27 L(P = 0.237),女性为 - 0.72±2.37 L(P = 0.06)。我们的方法至少在白种健康人群中,允许使用该FFI测量TBW,其准确性与全身多频医学阻抗仪相同,并且在直立位置进行的测量要快得多。