韩国男孩中DAO和DAOA基因多态性与自闭症谱系障碍的关联：一项初步研究。
Association of the DAO and DAOA gene polymorphisms with autism spectrum disorders in boys in Korea: a preliminary study.
作者信息
Chung Seockhoon, Hong Jin Pyo, Yoo Hanik K
机构信息
Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea.
出版信息
Psychiatry Res. 2007 Oct 31;153(2):179-82. doi: 10.1016/j.psychres.2007.02.007. Epub 2007 Jul 16.
We examined the association of autism spectrum disorders (ASD) with polymorphisms in the DAO and DAOA genes. The sample comprised 57 children with ASD, 47 complete trios, and 83 healthy controls in Korea. Although the transmission disequilibrium test showed no association, a population-based case-control study showed significant associations between the rs3918346 and rs3825251 SNPs of the DAO gene and boys with ASD.
我们研究了自闭症谱系障碍（ASD）与DAO和DAOA基因多态性之间的关联。样本包括57名患有ASD的韩国儿童、47个完整的三联体以及83名健康对照者。尽管传递不平衡检验未显示出关联，但一项基于人群的病例对照研究表明，DAO基因的rs3918346和rs3825251单核苷酸多态性（SNP）与患有ASD的男孩之间存在显著关联。
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