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奥氮平治疗急性精神病性发作的精神分裂症患者的疗效标准分析。

Analysis of resolution criteria in patients with schizophrenia treated with olanzapine for an acute psychotic episode.

作者信息

Peuskens Joseph, Kaufman Leonard, Van Vleymen Betty

机构信息

Universitair Psychiatrisch Centrum Katholieke Universiteit Leuven, Campus St. Jozef Kortenberg, Leuvensesteenweg 517, 3070 Kortenberg, Belgium.

出版信息

Schizophr Res. 2007 Sep;95(1-3):169-73. doi: 10.1016/j.schres.2007.05.035. Epub 2007 Jul 13.

DOI:10.1016/j.schres.2007.05.035
PMID:17630255
Abstract

Resolution was defined as achieving the severity component of the remission criteria (simultaneous ratings of mild or less on 8 of the PANSS items evaluating the core symptoms of schizophrenia). Analysis of a 6-week open label study with olanzapine 5-20 mg in 306 patients with acute exacerbation, shows resolution to be a clinically meaningful measure and an achievable outcome for treatment of acute psychosis.

摘要

缓解被定义为达到缓解标准的严重程度部分(在评估精神分裂症核心症状的8项阳性和阴性症状量表[PANSS]项目中同时评定为轻度或更低)。对306例急性加重患者使用5 - 20毫克奥氮平进行的为期6周的开放标签研究分析表明,缓解是一种具有临床意义的衡量指标,也是治疗急性精神病可实现的结果。

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引用本文的文献

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Clinical Global Impression-severity score as a reliable measure for routine evaluation of remission in schizophrenia and schizoaffective disorders.临床总体印象-严重程度评分作为精神分裂症和分裂情感性障碍缓解期常规评估的可靠指标。
Ann Gen Psychiatry. 2015 Feb 13;14:6. doi: 10.1186/s12991-015-0042-6. eCollection 2015.