Peuskens Joseph, Kaufman Leonard, Van Vleymen Betty
Universitair Psychiatrisch Centrum Katholieke Universiteit Leuven, Campus St. Jozef Kortenberg, Leuvensesteenweg 517, 3070 Kortenberg, Belgium.
Schizophr Res. 2007 Sep;95(1-3):169-73. doi: 10.1016/j.schres.2007.05.035. Epub 2007 Jul 13.
Resolution was defined as achieving the severity component of the remission criteria (simultaneous ratings of mild or less on 8 of the PANSS items evaluating the core symptoms of schizophrenia). Analysis of a 6-week open label study with olanzapine 5-20 mg in 306 patients with acute exacerbation, shows resolution to be a clinically meaningful measure and an achievable outcome for treatment of acute psychosis.
缓解被定义为达到缓解标准的严重程度部分(在评估精神分裂症核心症状的8项阳性和阴性症状量表[PANSS]项目中同时评定为轻度或更低)。对306例急性加重患者使用5 - 20毫克奥氮平进行的为期6周的开放标签研究分析表明,缓解是一种具有临床意义的衡量指标,也是治疗急性精神病可实现的结果。