Lysaker Paul H, Taylor Amanda C
Roudebush VA Medical Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Psychopathology. 2007;40(5):338-44. doi: 10.1159/000105532. Epub 2007 Jul 13.
Research has indicated that stable individual differences in personality exist among persons with schizophrenia, and that they likely predate the onset of illness. Less is known about whether individual differences in personality are related to levels of psychopathology and function.
This study tested the hypotheses that levels of neuroticism, extraversion and agreeableness are associated with symptomatology and coping in schizophrenia both concurrently and as measured 12 months later for 46 participants with schizophrenia or schizoaffective disorder. Baseline assessments were conducted, which included measurements of the personality dimensions of neuroticism, extraversion and agreeableness measured using the NEO, coping preferences using the Ways of Coping Questionnaire and symptoms using the Positive and Negative Syndrome Scale. The symptom and coping measures were repeated 12 months after the date of the baseline assessment.
Univariate correlations comparing baseline assessments suggested that higher neuroticism and lower extraversion were concurrently linked to more emotional discomfort and avoidant coping. Agreeableness was linked only to positive symptoms. Correlations controlling for baseline levels revealed greater levels of neuroticism at baseline, predicted a preference for resigning when under stress and higher emotional discomfort 12 months later. Lesser levels of agreeableness continued to predict greater positive symptoms 12 months later. No long-term associations were found between coping and symptoms at 12 months with levels of extraversion.
The results suggest individual differences in personality are associated with psychopathology in schizophrenia and may affect function over time. More research is needed with broader samples and with more frequent follow-up assessments.
研究表明,精神分裂症患者存在稳定的人格个体差异,且这些差异可能在疾病发作之前就已存在。关于人格个体差异是否与精神病理学水平和功能相关,人们了解较少。
本研究对46名精神分裂症或分裂情感性障碍患者进行了测试,以验证神经质、外向性和宜人性水平与精神分裂症症状及应对方式在当下以及12个月后的关联这一假设。进行了基线评估,包括使用大五人格量表测量神经质、外向性和宜人性等人格维度,使用应对方式问卷测量应对偏好,以及使用阳性和阴性症状量表测量症状。在基线评估日期12个月后重复进行症状和应对措施评估。
比较基线评估的单变量相关性表明,较高的神经质和较低的外向性与更多的情绪不适和回避应对同时存在关联。宜人性仅与阳性症状相关。控制基线水平的相关性显示,基线时较高的神经质水平预测了压力下倾向于屈服以及12个月后更高的情绪不适。较低的宜人性水平在12个月后继续预测更多的阳性症状。12个月时,外向性水平与应对方式和症状之间未发现长期关联。
结果表明,人格个体差异与精神分裂症的精神病理学相关,且可能随时间影响功能。需要对更广泛的样本进行更多研究,并进行更频繁的随访评估。