Hoffman Ralph E
Yale-New Haven Psychiatric Hospital, 184 Liberty Street, New Haven, CT 06519, USA.
Schizophr Bull. 2007 Sep;33(5):1066-70. doi: 10.1093/schbul/sbm079. Epub 2007 Jul 13.
The "social brain" of humans reflects widespread neural resources dedicated to understanding the conversational language, emotionality, states of mind, and intentions of other persons. A social deafferentation (SDA) hypothesis for induction of active schizophrenia is proposed. Analogous to hallucinations produced by sensory deafferentation, such as phantom limb, the SDA hypothesis assumes that high levels of social withdrawal/isolation in vulnerable individuals prompt social cognition programs to produce spurious social meaning in the form of complex, emotionally compelling hallucinations and delusions representing other persons or agents. Arguments against the SDA hypothesis are discussed, and predictions deriving from the hypothesis are offered.
人类的“社会脑”反映了广泛的神经资源,这些资源致力于理解对话语言、情感、他人的心理状态和意图。本文提出了一个关于引发活动性精神分裂症的社会去传入(SDA)假说。类似于感觉去传入所产生的幻觉,如幻肢,SDA假说认为,易患个体的高度社交退缩/隔离会促使社会认知程序产生虚假的社会意义,其形式为复杂的、情感上引人注目的幻觉和妄想,这些幻觉和妄想代表他人或主体。本文讨论了对SDA假说的反对观点,并给出了该假说的预测。