Richter Holly E, Nygaard Ingrid, Burgio Kathryn L, Handa Victoria L, Fitzgerald Mary Pat, Wren Patricia, Zyczynski Halina, Fine Paul, Brown Morton B, Weber Anne M
Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA.
J Urol. 2007 Sep;178(3 Pt 1):965-9; discussion 969. doi: 10.1016/j.juro.2007.05.045. Epub 2007 Jul 16.
We compared lower urinary tract and voiding symptoms in women with and without symptoms of stress urinary incontinence who were planning to undergo abdominal sacrocolpopexy for pelvic organ prolapse.
Subjects without stress urinary incontinence included 293 women in the Colpopexy and Urinary Reduction Efforts Trial. Subjects with stress urinary incontinence included 82 women who met trial inclusion criteria except for having stress urinary incontinence symptoms. We assessed symptoms and quality of life using validated measures.
After adjusting for age, race and site subjects with stress urinary incontinence had higher irritative and obstructive symptom subscale scores and reported greater symptom bother, greater impact of colorectal and prolapse symptoms, and poorer physical and mental health.
Women with prolapse and stress urinary incontinence had more lower urinary tract symptoms and reported more functional impact. This is contrary to our hypothesis that women with prolapse and stress urinary incontinence would have fewer irritative, obstructive and voiding symptoms because of the relief valve effect of the less resistant urethra.
我们比较了计划接受腹骶骨固定术治疗盆腔器官脱垂的有压力性尿失禁症状和无压力性尿失禁症状的女性的下尿路症状和排尿症状。
无压力性尿失禁的受试者包括293名参与阴道骶骨固定术和尿流减少试验的女性。有压力性尿失禁的受试者包括82名除有压力性尿失禁症状外符合试验纳入标准的女性。我们使用经过验证的方法评估症状和生活质量。
在对年龄、种族和研究地点进行校正后，有压力性尿失禁的受试者的刺激性和梗阻性症状子量表得分更高，报告的症状困扰更大，结肠直肠和脱垂症状的影响更大，身心健康状况更差。
患有脱垂和压力性尿失禁的女性有更多的下尿路症状，且报告的功能影响更大。这与我们的假设相反，即患有脱垂和压力性尿失禁的女性由于尿道阻力较小的安全阀效应，刺激性、梗阻性和排尿症状会更少。
