Etang Josiane, Chouaibou Mouhamadou, Toto Jean-Claude, Faye Ousmane, Manga Lucien, Samè-Ekobo Albert, Awono-Ambene Parfait, Simard Frédéric
Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale (OCEAC), P.O. Box 288, Yaoundé, Cameroun.
Trans R Soc Trop Med Hyg. 2007 Sep;101(9):881-4. doi: 10.1016/j.trstmh.2007.05.012. Epub 2007 Jul 16.
A trial of permethrin-treated nets (PTNs) versus untreated nets (UTNs) was conducted in Pitoa (north Cameroon), where the main malaria vectors, Anopheles gambiae s.l. and Anopheles arabiensis, show metabolic-based permethrin resistance. The deterrent effect of permethrin greatly reduced A. gambiae biting rate inside rooms where PTNs were installed. After 3 months of net use, malaria reinfection rate was significantly lower in children sleeping under a PTN, but no such effect was observed after 6 months. Parasitaemia was not significantly different between the two arms. These findings suggest good, although transitory, personal protection against malaria conferred by PTNs in an area of metabolic-based permethrin resistance.
在喀麦隆北部的皮托阿进行了一项经氯菊酯处理的蚊帐（PTN）与未处理蚊帐（UTN）的试验，当地主要的疟疾传播媒介冈比亚按蚊复合组和阿拉伯按蚊表现出基于代谢的氯菊酯抗性。氯菊酯的驱避作用大大降低了安装PTN的室内冈比亚按蚊的叮咬率。使用蚊帐3个月后，睡在PTN下的儿童疟疾再感染率显著降低，但6个月后未观察到这种效果。两组之间的寄生虫血症没有显著差异。这些发现表明，在一个存在基于代谢的氯菊酯抗性的地区，PTN对疟疾具有良好的（尽管是短暂的）个人防护作用。
