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接受苯妥英治疗患者的运动神经传导研究。

Motor nerve conduction study in patients on diphenylhydantoin therapy.

作者信息

Chokroverty S, Sayeed Z A

出版信息

J Neurol Neurosurg Psychiatry. 1975 Dec;38(12):1235-9. doi: 10.1136/jnnp.38.12.1235.

Abstract

Mean motor conduction velocity of posterior tibial nerves was significantly reduced in epileptic patients treated with diphenylhydantoin formore than 10 years or in patients with serum diphenylhydantoin level above 20 mug/ml. Subnormal serum folate was not responsible for this reduction and clinical peripheral neuropathy was infrequent.

摘要

使用苯妥英钠治疗超过10年的癫痫患者或血清苯妥英钠水平高于20μg/ml的患者,胫后神经的平均运动传导速度显著降低。血清叶酸水平低于正常并不导致这种降低,且临床周围神经病变并不常见。

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本文引用的文献

4
Effect of diphenylhydantoin on peripheral nerve.
Neurology. 1958 Feb;8(2):140-4. doi: 10.1212/wnl.8.2.140.
5
6
Sensory and motor nerve conduction velocity in long-term diphenylhydantoin therapy.
Arq Neuropsiquiatr. 1972 Sep;30(3):215-20. doi: 10.1590/s0004-282x1972000300002.
7
Nerve conduction velocity in patients on long-term diphenylhydantoin therapy.
Epilepsia. 1974 Jun;15(2):147-54. doi: 10.1111/j.1528-1157.1974.tb04938.x.
9
Peripheral neuropathy in long-term diphenylhydantoin therapy.
Arch Neurol. 1968 Jan;18(1):69-77. doi: 10.1001/archneur.1968.00470310083007.
10
Effect of diphenylhydantoin on peripheral nerves in man.
Electroencephalogr Clin Neurophysiol. 1968 Oct;25(4):411.

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