Chokroverty S, Sayeed Z A
J Neurol Neurosurg Psychiatry. 1975 Dec;38(12):1235-9. doi: 10.1136/jnnp.38.12.1235.
Mean motor conduction velocity of posterior tibial nerves was significantly reduced in epileptic patients treated with diphenylhydantoin formore than 10 years or in patients with serum diphenylhydantoin level above 20 mug/ml. Subnormal serum folate was not responsible for this reduction and clinical peripheral neuropathy was infrequent.
使用苯妥英钠治疗超过10年的癫痫患者或血清苯妥英钠水平高于20μg/ml的患者,胫后神经的平均运动传导速度显著降低。血清叶酸水平低于正常并不导致这种降低,且临床周围神经病变并不常见。