Maev I V, Merzlikin L A, Vorob'ev L P, Busarova G A
Sov Med. 1991(8):11-3.
The paper presents clinical and instrumental evidence on 47 patients with hepatic cirrhosis. The revealed ventilatory disorders and worse bronchial permeability closely correlated with the degree of pulmonary hypertension which in its turn depended on portal hypertension degree. Pulmonary hypertension decreased with a decline in the activity of the pathological process in the liver due to treatment. External respiration insufficiency observed in hepatic cirrhosis contributes to the onset of arterial hypoxemia and hypoxic impairment of the liver activating in it a pathological process. It is recommended that such patients should receive a combined treatment incorporating oxygen therapy, calcium antagonists, antioxidants.
该论文展示了47例肝硬化患者的临床和仪器检查证据。所发现的通气障碍和较差的支气管通透性与肺动脉高压程度密切相关,而肺动脉高压又取决于门静脉高压程度。由于治疗,随着肝脏病理过程活动度的下降,肺动脉高压也降低。肝硬化中观察到的外呼吸功能不全导致动脉血氧不足和肝脏的缺氧损伤,从而激活肝脏中的病理过程。建议此类患者接受包括氧疗、钙拮抗剂、抗氧化剂在内的综合治疗。