Khalifa M, Kaabia N, Gannouchi N, Sriha B, Bahri F, Letaief O A
CHU Farhat Hached, Service de Médecine Interne et Maladies Infectieuses, 4000 Sousse Tunisie.
Rev Laryngol Otol Rhinol (Bord). 2007;128(1-2):117-9.
Kikuchi-Fujimoto's is a rare disease, characterized by the diversity of clinical symptoms, with predominance of enlarged cervical lymph nodes and fever. We report three cases with different presentations.
The first one was a classic form, frequently described in literature. The second was characterized by concomitant association with systemic lupus erythematosus. Histologic findings of Kikuchi's disease were the presence of nuclear debris, absence of haemathoxilin bodies and neutrophils polynuclears. The presentation of the third case was acute meningitis with cervical lymphadenopathy. Lumber puncture showed lymphocytic meningitis, mild hypoglycorrhachia and hyperproteinrrhachia. Favourable evolution was noted in all cases without recurrence.
Wathever its presentation the prognosis of the Kikuchi-Fujimoto's disease is generally benign with a spontaneously favorable evolution between 1 to 6 months.
菊池-藤本病是一种罕见疾病，临床症状多样，以颈部淋巴结肿大和发热为主。我们报告三例表现各异的病例。
第一例为文献中常见描述的经典类型。第二例的特征是合并系统性红斑狼疮。菊池病的组织学表现为存在核碎片、无苏木精小体和多核中性粒细胞。第三例表现为急性脑膜炎伴颈部淋巴结病。腰椎穿刺显示淋巴细胞性脑膜炎、轻度脑脊液低糖和高蛋白。所有病例病情进展良好，无复发。
无论菊池-藤本病表现如何，其预后通常良好，在1至6个月内可自发好转。
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