Bumbasirević V, Jovanović B, Palibrk I, Karamarković A, Radenković D, Gregorić P, Djukić V, Stevanović R, Simić D, Ivancević N
Institut za anesteziju i reanimatologiju,Urgentni centar KCS, Beograd.
Acta Chir Iugosl. 2007;54(1):63-70. doi: 10.2298/aci0701063b.
Hemorrhagic shock is a condition produced by rapid and significant loss of blood which lead to hemodynamic instability, decreases in oxygen delivery, decreased tissue perfusion, cellular hypoxia, organ damage and can be rapidly fatal. Despite improved understanding of the pathophysiology and significant advances in technology, it remains a serious problem associated with high morbidity and mortality. Early treatment is essential but is hampered by the fact that signs and symptoms of shock appear only after the state of shock is well establish and the compensatory mechanisms have started to fail. The primary goal is to stop the bleeding and restore the intravascular volume. This review addresses the pathophysiology and treatment of haemorrhagic shock.
失血性休克是一种由于快速且大量失血导致的病症,会引发血流动力学不稳定、氧输送减少、组织灌注降低、细胞缺氧、器官损伤,并且可能迅速致命。尽管对其病理生理学的理解有所改善,技术也取得了显著进步,但它仍然是一个与高发病率和死亡率相关的严重问题。早期治疗至关重要,但受到休克的体征和症状仅在休克状态充分确立且代偿机制开始失效后才出现这一事实的阻碍。首要目标是止血并恢复血管内容量。本综述探讨失血性休克的病理生理学和治疗方法。