Lemajić-Komazec Slobodanka, Komazec Zoran
Klinika za bolesti uva, grla i nosa, Klinicki centar "Novi Sad", Novi Sad.
Med Pregl. 2006 Nov-Dec;59(11-12):585-90. doi: 10.2298/mpns0612585l.
Dizziness is one of the most common reasons patients visit their physicians. Balance control depends on receiving afferent sensory information from several sensory systems: vestibular, optical and proprioceptive. Bioelectric signals, generated by body movements in the semicircular canals and in the otolithic apparatus, are transported via the vestibular nerve to the vestibular nucleus. All four vestibular nuclei, located bilaterally in medial longitudinal fasciculus, are linked with central nervous system structures. These central nervous system structures are involved in maintaining visual stability, spatial orientation and balance control. Nystagmus is a result of afferent signals balance disorders. Nystagmus due to peripheral lesions is conjugate nystagmus, because there is a bilateral central connection. Lesions above the vestibular nuclei induce deficits in synchronization and conjugation of eye movements, thus the nystagmus is dissociated. This paper shows that in peripheral vestibular disorders spontaneous nystagmus is rhythmic, associated, horizontal-rotatory or horizontal, with subjective sensation of dizziness which decreases with time and harmonic signs whose direction coincides with the slow phase of nystagmus and it is associated with mild disorders during pendular stimulation with statistically significant vestibular hypofunction. Spontaneous nystagmus in central vestibular lesions is severe, dissociated, horizontal, rotatory or vertical, without changes related to optical suppression; if vestibular symptoms are present, they are non-harmonic. In central disorders, findings after thermal stimulation are either normal or pathological, with dysrhythmias and inhibition in pendular stimulation. This paper deals with differential diagnosis of vertigo based on anamnesis and clinical examination, as well as objective diagnostic tests.
头晕是患者就医最常见的原因之一。平衡控制依赖于从多个感觉系统接收传入的感觉信息:前庭、视觉和本体感觉。由半规管和耳石器官中的身体运动产生的生物电信号通过前庭神经传输到前庭核。所有四个前庭核双侧位于内侧纵束中,与中枢神经系统结构相连。这些中枢神经系统结构参与维持视觉稳定性、空间定向和平衡控制。眼球震颤是传入信号平衡障碍的结果。外周病变引起的眼球震颤是共轭性眼球震颤,因为存在双侧中枢连接。前庭核以上的病变会导致眼球运动同步和共轭方面的缺陷,因此眼球震颤是分离性的。本文表明,在外周前庭疾病中,自发性眼球震颤是有节律的、相关的、水平旋转性或水平性的,伴有头晕的主观感觉,这种感觉会随着时间而减轻,且调和征的方向与眼球震颤的慢相一致,并且在摆动刺激期间与轻度疾病相关,伴有统计学上显著的前庭功能减退。中枢前庭病变中的自发性眼球震颤严重、分离、水平、旋转或垂直,与视觉抑制无关;如果存在前庭症状,则是非调和性的。在中枢性疾病中,热刺激后的结果要么正常要么异常,在摆动刺激时出现节律异常和抑制。本文讨论了基于病史和临床检查以及客观诊断测试的眩晕鉴别诊断。