Pascual Samaniego M, González Núñez M A, Bravo Fernández I, Ruiz Serrano M, Ramos Martín J A, García González A
Servicios de Urología, Hospital San Pedro de Alcántara, Cáceres.
Actas Urol Esp. 2007 Apr;31(4):404-10. doi: 10.1016/s0210-4806(07)73656-2.
Papillary renal cell carcinoma has been related with higher survival rate and lower metastatic cancer mortality rate than clear renal cell carcinoma. We present an aggressive case related to unusual features for this histological type, like a tumor size higher than ten cm, great perirrenal fat and suprarenal gland infiltration, tumoral thrombosis of the infrahepatic cava vein, retroperitoneal adenopatic tumoral infiltration, high nuclear grade and synchronous solitary distant organ metastases of the right spermatic cord, finding three previous cases in the literature with this last feature. Prognostic implication of the papillary renal cell carcinoma type is unclear in cases like this, so probably we need better molecular and cytogenetic studies to get a correct classification of this histological type.
与透明肾细胞癌相比，乳头状肾细胞癌的生存率更高，转移性癌症死亡率更低。我们报告了一例具有该组织学类型不寻常特征的侵袭性病例，如肿瘤大小超过10厘米、肾周脂肪大量浸润和肾上腺浸润、肝下腔静脉肿瘤血栓形成、腹膜后淋巴结肿瘤浸润、高核分级以及右侧精索同步孤立性远处器官转移，在文献中发现此前有三例具有这最后一个特征的病例。在这样的病例中，乳头状肾细胞癌类型的预后意义尚不清楚，所以可能我们需要更好的分子和细胞遗传学研究来对这种组织学类型进行正确分类。
