Xin-Xing Feng, Li-Li Zhang, Jian-Yong Chen, Hua-Peng Zhang
The State Key Laboratory of Polymer Materials Engineering, Polymer Research Institute of Sichuan University, Chengdu, 610065, People's Republic of China.
J Biomed Mater Res A. 2008 Mar 1;84(3):761-8. doi: 10.1002/jbm.a.31258.
By sol-gel processing, the regenerated nano-TiO(2)/SF (silk fibroin) hybrid films were synthesized using different ratios of TiO(2) to SF. The experimental results revealed that the nano-TiO(2) particles were well dispersed in the regenerated SF. The diameter of the nano-TiO(2) particles processed by sol-gel method was about 80 nm. Through Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), X-ray energy dispersive spectrometer (EDS), Thermogravimetric analysis (TGA), and Derivative thermogravimetry (DTG), the structures and properties of these hybrid films were characterized. The XRD measurement indicated that the crystal structures of the hybrid films were transited from typical Silk I to typical Silk II. However, it was found that excessive increase in the content of nano-TiO(2) led to the breakage of the crystal structures of the hybrid films. The FTIR and EDS analysis showed that new bonds were formed between the nano-TiO(2) particles and the SF. Through TGA and DTG, it was demonstrated that the heat transition temperature of the hybrid films was also enhanced.
通过溶胶-凝胶法，使用不同比例的TiO₂与丝素蛋白（SF）合成了再生纳米TiO₂/SF杂化薄膜。实验结果表明，纳米TiO₂颗粒在再生丝素蛋白中分散良好。通过溶胶-凝胶法制备的纳米TiO₂颗粒直径约为80nm。通过傅里叶变换红外光谱（FTIR）、X射线衍射（XRD）、X射线能量色散谱仪（EDS）、热重分析（TGA）和微商热重分析（DTG）对这些杂化薄膜的结构和性能进行了表征。XRD测量表明，杂化薄膜的晶体结构从典型的丝素I转变为典型的丝素II。然而，发现纳米TiO₂含量的过度增加导致杂化薄膜晶体结构的破坏。FTIR和EDS分析表明，纳米TiO₂颗粒与丝素蛋白之间形成了新的键。通过TGA和DTG表明，杂化薄膜的热转变温度也有所提高。
