Ricci D, Vasco G, Baranello G, Salerni A, Amante R, Tamburrini G, Dickmann A, Di Rocco C, Velardi F, Mercuri E
Pediatric Neurology Unit, Catholic University, Rome, Italy.
Dev Med Child Neurol. 2007 Aug;49(8):574-6. doi: 10.1111/j.1469-8749.2007.00574.x.
The aim of this study was to assess various aspects of visual function in children with single-suture, non-syndromic craniosynostosis. Thirty-eight infants (28 males, 10 females; age range 3.5-13mo, mean age 7mo, 11 with plagiocephaly, 12 with trigonocephaly, and 15 with scaphocephaly), were assessed with a battery of tests specifically designed to assess various aspects of visual function in infancy. Thirty-two of the 38 infants had at least one abnormality on one of the aspects of visual function assessed. Abnormal eye movements were found in eight infants of the whole cohort and were mainly found in infants with plagiocephaly (6/11), who also had frequent visual field abnormalities (5/11). In contrast, fixation shift, an aspect of visual function related to the integrity of parietal lobes, was more frequently abnormal in patients with scaphocephaly. Our results suggest that the presence and severity of visual impairment is related to the type of craniosynostosis. Follow-up studies after surgical correction are needed to evaluate the possible beneficial effects of reconstructive surgery on visual function.
本研究的目的是评估单缝、非综合征性颅缝早闭患儿视觉功能的各个方面。38名婴儿（28名男性，10名女性；年龄范围3.5 - 13个月，平均年龄7个月，11例为扁头畸形，12例为三角头畸形，15例为舟状头畸形）接受了一系列专门设计用于评估婴儿期视觉功能各个方面的测试。38名婴儿中有32名在评估的视觉功能方面至少有一项异常。在整个队列的8名婴儿中发现了异常眼动，主要见于扁头畸形婴儿（6/11），这些婴儿也经常有视野异常（5/11）。相比之下，与顶叶完整性相关的视觉功能方面——注视转移，在舟状头畸形患者中更常出现异常。我们的结果表明，视力损害的存在和严重程度与颅缝早闭的类型有关。需要在手术矫正后进行随访研究，以评估重建手术对视觉功能可能产生的有益影响。
