透析患者中的病毒性肝炎感染：泰国登记报告。

Viral hepatitis infections among dialysis patients: Thailand registry report.

作者信息

Thanachartwet Vipa, Phumratanaprapin Weerapong, Desakorn Varunee, Sahassananda Duangjai, Wattanagoon Yupaporn, Chaiprasert Amnart, Aimpun Pote, Supaporn Thanom

机构信息

Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

出版信息

Nephrology (Carlton). 2007 Aug;12(4):399-405. doi: 10.1111/j.1440-1797.2007.00815.x.

DOI:10.1111/j.1440-1797.2007.00815.x

PMID:17635757

Abstract

BACKGROUND

Patients on dialysis are at high risk of acquiring viral hepatitis infections. However, there were only few data from Thailand. The aim of the present study was to assess the prevalence, incidence and associated risk factors of viral hepatitis infections among dialysis patients.

METHODS

A retrospective study was conducted to evaluate 5179 medical records of dialysis patients from the Thailand Renal Replacement Therapy Registry.

RESULTS

In 2002, the seroprevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections were 6.3% (n = 2454) and 4.8% (n = 2167), respectively. HBV and HCV seroprevalence became 6.5% (n = 2585) and 4.3% (n = 2399) in 2003. The incidence of HBV and HCV infections were 1.5 and 2.4 cases per 1000 patient-years, respectively. Logistic regression analysis showed that age and gender were significant risk factors for HBV infection, but not for HCV infection.

CONCLUSION

In Thailand, it was not uncommon for dialysis patients to acquire viral hepatitis infections. However, our prevalence is similar to reports from some other South-East Asian countries.

摘要

背景

透析患者感染病毒性肝炎的风险很高。然而，来自泰国的数据很少。本研究的目的是评估透析患者中病毒性肝炎感染的患病率、发病率及相关危险因素。

方法

进行一项回顾性研究，以评估泰国肾脏替代治疗登记处5179例透析患者的病历。

结果

2002年，乙肝病毒（HBV）和丙肝病毒（HCV）感染的血清流行率分别为6.3%（n = 2454）和4.8%（n = 2167）。2003年，HBV和HCV血清流行率分别为6.5%（n = 2585）和4.3%（n = 2399）。HBV和HCV感染的发病率分别为每1000患者年1.5例和2.4例。逻辑回归分析表明，年龄和性别是HBV感染的重要危险因素，但不是HCV感染的危险因素。