Naganuma Toshihide, Uchida Junji, Kinoshita Yoshihisa, Kuroki Yoshikazu, Takemoto Yoshiaki, Yoshimura Rikio, Sugimura Kazunobu, Nakatani Tatsuya
Department of Urology, Osaka City University Medical School, Osaka, Japan.
Nephrology (Carlton). 2007 Aug;12(4):413-7. doi: 10.1111/j.1440-1797.2007.00791.x.
The prevalence of metabolic syndrome (MS) after renal transplantation has yet to be elucidated. In the present study, we investigated the prevalence of MS in Japanese renal transplant recipients.
A cross-sectional study was conducted to determine the prevalence of MS in 101 renal transplant recipients at Osaka City University Hospital. The prevalence of MS was determined using the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATPIII) criteria (modified and original) and the International Diabetes Federation (IDF) criteria.
Using the modified (Japanese) NCEP criteria, a total of 24 out of 101 patients (23.8%) had MS including 21 out of 64 male patients (32.8%) and three out of 37 female patients (8.1%). Using the modified (Asian) NCEP criteria, MS was diagnosed in 23 patients (22.8%); 19 male (29.7%) and four female (10.8%). Using the original NCEP criteria, MS was diagnosed in 15 patients (14.9%); 12 male (18.8%) and three female (8.1%). Using the IDF criteria, MS was diagnosed in 16 patients (15.8%); 15 male (23.4%) and one female (2.7%).
The prevalence of MS differed according to the NCEP criteria used, which had different cut-off points for waist circumference (14.9-23.8%). By the IDF criteria, which cites central obesity as an essential component, the prevalence of MS was slightly lower. Furthermore, in our study, MS was more prevalent in male renal transplant recipients.
肾移植后代谢综合征(MS)的患病率尚未明确。在本研究中,我们调查了日本肾移植受者中MS的患病率。
进行了一项横断面研究,以确定大阪市立大学医院101名肾移植受者中MS的患病率。采用美国国家胆固醇教育计划成人治疗组第三次报告(NCEP-ATPIII)标准(修订版和原版)以及国际糖尿病联盟(IDF)标准来确定MS的患病率。
采用修订后的(日本版)NCEP标准,101例患者中有24例(23.8%)患有MS,其中64例男性患者中有21例(32.8%),37例女性患者中有3例(8.1%)。采用修订后的(亚洲版)NCEP标准,23例患者(22.8%)被诊断为MS;19例男性(29.7%)和4例女性(10.8%)。采用原版NCEP标准,15例患者(14.9%)被诊断为MS;12例男性(18.8%)和3例女性(8.1%)。采用IDF标准,16例患者(15.8%)被诊断为MS;15例男性(23.4%)和1例女性(2.7%)。
根据所使用的NCEP标准不同,MS的患病率也有所不同,这些标准对腰围的切点不同(14.9%-23.8%)。根据将中心性肥胖作为基本组成部分的IDF标准,MS的患病率略低。此外,在我们的研究中,男性肾移植受者中MS更为普遍。