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健康儿童补充钙不会影响体重增加、身高或身体成分。

Calcium supplements in healthy children do not affect weight gain, height, or body composition.

作者信息

Winzenberg Tania, Shaw Kelly, Fryer Jayne, Jones Graeme

机构信息

Menzies Research Institute, Private Bag 23, Hobart, TAS 7001 Australia.

出版信息

Obesity (Silver Spring). 2007 Jul;15(7):1789-98. doi: 10.1038/oby.2007.213.

Abstract

OBJECTIVE

Calcium intake is a potential factor influencing weight gain and may reduce body weight, but the evidence for this in children is conflicting. The aim of this study was to use data from randomized controlled trials to determine whether calcium supplementation in healthy children affects weight or body composition.

RESEARCH METHODS AND PROCEDURES

This study is a systematic review. We identified potential studies by searching the following electronic bibliographic databases: CENTRAL, MEDLINE, EMBASE, CINAHL, AMED, MANTIS, ISI Web of Science, Food Science and Technology Abstracts, and Human Nutrition up until April 1, 2005 and hand-searched relevant conference abstracts. Studies were included if they were placebo-controlled randomized controlled trials of calcium supplementation, with at least 3 months of supplementation, in healthy children and with outcome measures including weight. Meta-analyses were performed using fixed effects models and weighted mean differences for weight and height and standardized mean differences (SMDs) for body composition measures.

RESULTS

There were no statistically significant effects of calcium supplementation on weight [+0.14 kg; 95% confidence interval (CI), -0.28, +0.57 kg], height (+0.22 cm; 95% CI, -0.30, +0.74 cm), body fat (SMD, +0.04; 95% CI, -0.08, +0.15), or lean mass (SMD, +0.14; 95% CI, -0.03, +0.31).

DISCUSSION

There is no evidence to support the use of calcium supplementation as a public health intervention to reduce weight gain or body fat in healthy children. Although our results do not rule out an effect of dietary supplementation with dairy products on weight gain or body composition, there is little evidence to support this hypothesis.

摘要

目的

钙摄入量是影响体重增加的一个潜在因素,可能会减轻体重,但有关儿童的这方面证据存在矛盾。本研究的目的是利用随机对照试验的数据来确定健康儿童补充钙是否会影响体重或身体成分。

研究方法与步骤

本研究为系统评价。我们通过检索以下电子文献数据库来识别潜在的研究:截至2005年4月1日的Cochrane系统评价数据库、医学索引数据库、荷兰医学文摘数据库、护理学与健康领域数据库、联合和补充医学数据库、循证医学数据库、科学引文索引数据库、食品科学与技术文摘数据库以及人类营养数据库,并手工检索了相关会议摘要。纳入的研究需为补充钙的安慰剂对照随机对照试验,对象为健康儿童,补充时间至少3个月,且结局指标包括体重。采用固定效应模型进行荟萃分析,计算体重和身高的加权均数差以及身体成分指标的标准化均数差(SMD)。

结果

补充钙对体重[+0.14千克;95%置信区间(CI),-0.28,+0.57千克]、身高(+0.22厘米;95%CI,-0.30,+0.74厘米)、体脂(SMD,+0.04;95%CI,-0.08,+0.15)或瘦体重(SMD,+0.14;95%CI,-0.03,+0.31)均无统计学显著影响。

讨论

没有证据支持将补充钙作为一种公共卫生干预措施来减少健康儿童的体重增加或体脂。虽然我们的结果不排除食用乳制品进行膳食补充对体重增加或身体成分有影响,但几乎没有证据支持这一假设。

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